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Thermo Scientific Chemicals 3'-Azido-3'-deoxythymidine, 98%
Anti-viral agent
Supplier: Thermo Scientific Chemicals J6512714
Description
3'-Azido-3'-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against HIV-1 virus that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3?-Azido-3?-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications3′-Azido-3′-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against HIV-1 virus that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3′-Azido-3′-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening.
Solubility
Soluble in water.
Notes
Light Sensitive & Hygroscopic. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
Specifications
| 3'-Azido-3'-deoxythymidine | |
| 113°C to 115°C | |
| C10H13N5O4 | |
| 25 g | |
| Light sensitive; Very Hygroscopic | |
| azt; azidothymidine; zdv; zidovudine, 1-2r-4-azido-5-hydroxymethyl oxolan-2-yl-5-methyl-3h-pyrimidine-2,4-dione | |
| HBOMLICNUCNMMY-CFQLRCIDNA-N | |
| 1-[(2R,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione | |
| 455007 | |
| 98% |
| 30516-87-1 | |
| White | |
| MFCD00006536 | |
| 3595791 | |
| 1410123 | |
| Soluble in water. | |
| CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O | |
| 267.25 | |
| 267.24 | |
| Powder |
Chemical Identifiers
| 30516-87-1 | |
| 267.25 | |
| HBOMLICNUCNMMY-CFQLRCIDNA-N | |
| 455007 |
| C10H13N5O4 | |
| MFCD00006536 | |
| azt; azidothymidine; zdv; zidovudine, 1-2r-4-azido-5-hydroxymethyl oxolan-2-yl-5-methyl-3h-pyrimidine-2,4-dione | |
| CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O |
Safety and Handling
Causes serious eye irritation, Suspected of causing genetic defects, May cause respiratory irritation, Suspected of causing cancer, Causes skin irritation
Serious eye damage/eye irritation (category 2), Germ cell mutagenicity (category 2), Specific target organ toxicity after single exposure (category 3), Carcinogenicity (category 2), Skin corrosion/irritation (category 2)
RTECSNumber : XP207200
TSCA : No
Recommended Storage : Store at -20°C
RUO – Research Use Only