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1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%
CAS: 25952-53-8 | C8H18ClN3 | 191.70 g/mol
Supplier: Thermo Scientific Chemicals A1080703
Description
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.
Solubility
Soluble in acetonitrile dichloromethane, dimethylformamide, and tetrahydrofuran. Slightly soluble in water.
Notes
Sensitive to moisture. Incompatible with strong acids, strong oxidizing agents and moisture.
Specifications
| 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride | |
| ∽113°C | |
| CH3CH2N=C=N(CH2)3N(CH3)2·HCl | |
| 1 g | |
| Moisture sensitive | |
| Soluble in acetonitrile dichloromethane,dimethylformamide,and tetrahydrofuran. Slightly soluble in water. | |
| Cl.CCN=C=NCCCN(C)C | |
| 191.70 | |
| 191.7 |
| 25952-53-8 | |
| C8H18ClN3 | |
| MFCD00012503 | |
| 5764110 | |
| 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride, edc.hcl, edci, edc hydrochloride, wsc hcl, edac hydrochloride, edac, hydrochloride, 1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride, edcl, edac hcl | |
| FPQQSJJWHUJYPU-UHFFFAOYSA-N | |
| 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine;hydrochloride | |
| 2723939 | |
| ≥98% |
Chemical Identifiers
| 25952-53-8 | |
| 191.70 | |
| FPQQSJJWHUJYPU-UHFFFAOYSA-N | |
| 2723939 | |
| Cl.CCN=C=NCCCN(C)C |
| C8H18ClN3 | |
| MFCD00012503 | |
| 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride, edc.hcl, edci, edc hydrochloride, wsc hcl, edac hydrochloride, edac, hydrochloride, 1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride, edcl, edac hcl | |
| 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine;hydrochloride |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P272-P280-P301+P312-P302+P352-P305+P351+P338-P330-P333+P313-P362-P501c
H302-H315-H317-H319
DOTInformation : Hazard Class: 9; Packaging Group: III
EINECSNumber : 247-361-2
RTECSNumber : FF2200000
TSCA : Yes
Recommended Storage : Keep cold
RUO – Research Use Only