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1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane, 97%
CAS: 69304-37-6 | C12H28Cl2OSi2 | 315.425 g/mol
Supplier: Thermo Scientific Chemicals L1117106
Description
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane is a silylating reagent used for simultaneous protection of 3'- and 5'-hydroxy functions of ribonucleosides. It is used in the analysis of Watson-Crick and Hoogstein base pairing in nucleotides. It is also employed in the formation of ribavirin chemical delivery systems. Further, it serves as a protecting group reagent for open-chain polyhydroxy compounds. In addition to this, it is involved in the preparation of cyclic bridged peptides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane is a silylating reagent used for simultaneous protection of 3′- and 5′-hydroxy functions of ribonucleosides. It is used in the analysis of Watson-Crick and Hoogstein base pairing in nucleotides. It is also employed in the formation of ribavirin chemical delivery systems. Further, it serves as a protecting group reagent for open-chain polyhydroxy compounds. In addition to this, it is involved in the preparation of cyclic bridged peptides.
Solubility
Miscible with dimethylformamide, hexane, ethyl acetate, chloroform and dichloromethane.
Notes
Incompatible with strong oxidizing agents and water.
Specifications
| 69°C to 70°C (0.5mmHg) | |
| 69304-37-6 | |
| C12H28Cl2OSi2 | |
| UN1760 | |
| >110°C (230°F) | |
| Miscible with dimethylformamide,hexane,ethyl acetate,chloroform and dichloromethane. | |
| CC(C)[Si](C(C)C)(O[Si](C(C)C)(C(C)C)Cl)Cl | |
| 315.425 | |
| 315.43 | |
| 1.454 | |
| 0.986 |
| 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane | |
| 5 g | |
| MFCD00009655 | |
| 1934216 | |
| 1,3-dichloro-1,1,3,3-tetraisopropyldisiloxane, 1,3-dichlorotetraisopropyldisiloxane, 1,1,3,3-tetraisopropyl-1,3-dichlorodisiloxane, 1,3-dichloro-1,1,3,3-tetraisopropyl-disiloxane, disiloxane, 1,3-dichloro-1,1,3,3-tetrakis 1-methylethyl, 1,1,3,3-tetraisopropyl-1,3-dichlorosiloxane, chloro chlorodiisopropylsilyl oxy diisopropylsilane, chloro-chloro-di propan-2-yl silyl oxy-di propan-2-yl silane, tipdsicl2, tipdsi-cl2 | |
| DDYAZDRFUVZBMM-UHFFFAOYSA-N | |
| chloro-[chloro-di(propan-2-yl)silyl]oxy-di(propan-2-yl)silane | |
| 172404 | |
| 97% | |
| Moisture sensitive |
Chemical Identifiers
| 69304-37-6 | |
| 315.425 | |
| DDYAZDRFUVZBMM-UHFFFAOYSA-N | |
| 172404 | |
| CC(C)[Si](C(C)C)(O[Si](C(C)C)(C(C)C)Cl)Cl |
| C12H28Cl2OSi2 | |
| MFCD00009655 | |
| 1,3-dichloro-1,1,3,3-tetraisopropyldisiloxane, 1,3-dichlorotetraisopropyldisiloxane, 1,1,3,3-tetraisopropyl-1,3-dichlorodisiloxane, 1,3-dichloro-1,1,3,3-tetraisopropyl-disiloxane, disiloxane, 1,3-dichloro-1,1,3,3-tetrakis 1-methylethyl, 1,1,3,3-tetraisopropyl-1,3-dichlorosiloxane, chloro chlorodiisopropylsilyl oxy diisopropylsilane, chloro-chloro-di propan-2-yl silyl oxy-di propan-2-yl silane, tipdsicl2, tipdsi-cl2 | |
| chloro-[chloro-di(propan-2-yl)silyl]oxy-di(propan-2-yl)silane |
Safety and Handling
GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.
P210-P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P374-P501c
H227-H314
DOTInformation : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUIDS, N.O.S.
EINECSNumber : 000-000-0
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only