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Thermo Scientific Chemicals Vancomycin hydrochloride, Molecular Biology Grade

Vancomycin hydrochloride (vancomycin HCl, CAS # 1404-93-9) is the hydrochloride salt of the bactericidal agent, vancomycin. | CAS: 1404-93-9 | C66H76Cl3N9O24 | 1485.72 g/mol

$282.45 - $609.03

Chemical Identifiers

CAS 1404-93-9
Molecular Formula C66H76Cl3N9O24
Molecular Weight (g/mol) 1485.72
MDL Number MFCD03613611,MFCD03613611
InChI Key LCTORFDMHNKUSG-UHFFFAOYNA-N
PubChem CID 124080918
IUPAC Name 48-({3-[(4-amino-5-hydroxy-4,6-dimethyloxan-2-yl)oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl}oxy)-22-(carbamoylmethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2³,⁶.2¹⁴,¹⁷.1⁸,¹².1²⁹,³³.0¹⁰,²⁵.0³⁴,³⁹]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride
SMILES Cl.CNC(CC(C)C)C(=O)NC1C(O)C2=CC(Cl)=C(OC3=CC4=CC(OC5=C(Cl)C=C(C=C5)C(O)C5NC(=O)C(NC(=O)C4NC(=O)C(CC(N)=O)NC1=O)C1=CC(=C(O)C=C1)C1=C(O)C=C(O)C=C1C(NC5=O)C(O)=O)=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1)C=C2
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AAJ6279003
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Thermo Scientific Chemicals
J6279003
1 g
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AAJ6279006
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Thermo Scientific Chemicals
J6279006
5 g
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Description

Description

Inhibits bacterial mucopeptide synthesis.Vancomycin hydrochloride is used as an antiviral and anti bacterial. binds to bacterial cell wall. It exhibits potent activity against Gram positive bacteria and is highly effective against MRSA.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Vancomycin hydrochloride is a glycopeptide antibiotic that prevents cell wall synthesis
  • Originally obtained from the bacterial strain Streptomyces Orientalis
  • Vancomycin binds to D-alanyl-D-alanine motifs in cell wall precursors and leads to cell death
  • It is active against some penicillin-resistant bacteria

Application

  • Vancomycin hydrochloride is intended for use in the research of infections and for antibiotic resistance testing
Specifications

Chemical Identifiers

1404-93-9
1485.72
LCTORFDMHNKUSG-UHFFFAOYNA-N
48-({3-[(4-amino-5-hydroxy-4,6-dimethyloxan-2-yl)oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl}oxy)-22-(carbamoylmethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2³,⁶.2¹⁴,¹⁷.1⁸,¹².1²⁹,³³.0¹⁰,²⁵.0³⁴,³⁹]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride
C66H76Cl3N9O24
MFCD03613611,MFCD03613611
124080918
Cl.CNC(CC(C)C)C(=O)NC1C(O)C2=CC(Cl)=C(OC3=CC4=CC(OC5=C(Cl)C=C(C=C5)C(O)C5NC(=O)C(NC(=O)C4NC(=O)C(CC(N)=O)NC1=O)C1=CC(=C(O)C=C1)C1=C(O)C=C(O)C=C1C(NC5=O)C(O)=O)=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1)C=C2

Specifications

Vancomycin Hydrochloride
1404-93-9
1 g
C66H76Cl3N9O24
3704657
Soluble in water; Slightly soluble in methanol,ethanol and dimethylsulfoxide.
Cl.CNC(CC(C)C)C(=O)NC1C(O)C2=CC(Cl)=C(OC3=CC4=CC(OC5=C(Cl)C=C(C=C5)C(O)C5NC(=O)C(NC(=O)C4NC(=O)C(CC(N)=O)NC1=O)C1=CC(=C(O)C=C1)C1=C(O)C=C(O)C=C1C(NC5=O)C(O)=O)=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1)C=C2
1485.72
1485.73
Vancomycin hydrochloride
Powder
White
Hygroscopic
MFCD03613611,MFCD03613611
149929
LCTORFDMHNKUSG-UHFFFAOYNA-N
48-({3-[(4-amino-5-hydroxy-4,6-dimethyloxan-2-yl)oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl}oxy)-22-(carbamoylmethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2³,⁶.2¹⁴,¹⁷.1⁸,¹².1²⁹,³³.0¹⁰,²⁵.0³⁴,³⁹]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride
124080918
Molecular Biology
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Safety and Handling

Safety and Handling

Causes serious eye irritation, May cause respiratory irritation, May cause an allergic skin reaction, Causes skin irritation

Serious eye damage/eye irritation (category 2), Specific target organ toxicity after single exposure (category 3), Skin sensitisation (category 1), Skin corrosion/irritation (category 2)

RTECSNumber : YW4380000

TSCA : No

Recommended Storage : Keep cold

SDS
missing translation for 'documents'

missing translation for 'documents'

RUO – Research Use Only