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  6. Thermo Scientific Chemicals uPA Inhibitor II, UK122

Thermo Scientific Chemicals uPA Inhibitor II, UK122

Catalog No. p-7082431
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Catalog No. Quantity
AAJ64874LB0 5 mg
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Catalog No. AAJ64874LB0 Supplier Thermo Scientific Chemicals Supplier No. J64874LB0
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Description

A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activatoruPA Inhibitor II, UK122 acts as a potent, selective and active-site targeting urokinase-type plasminogen activator (uPA) inhibitor. However, its activity against trypsin, thrombin, tPA, and plasmin is greatly reduced. It is also effectively inhibits the migration (80% inhibition) and invasion (68% inhibition) of uPA-expressing CFPAC-1 pancreatic cells, without affecting its proliferation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

  • A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activator

Specifications

Quantity 5 mg
Description Yellow
Content And Storage 2°C to 8°C
For Use With (Application) A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activator
Molecular Formula C17H13N3O2·CF3CO2H
Formula Weight 405.30g/mol
Sensitivity Light Sensitive
Product Type Signal Transduction Reagent
Form Solid

RUO – Research Use Only