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Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water

CAS: 51805-45-9 | C9H12O6P | 247.16 g/mol

$108.56 - $1359.29

Chemical Identifiers

CAS 51805-45-9
Molecular Formula C9H12O6P
Molecular Weight (g/mol) 247.16
MDL Number MFCD00145469
InChI Key PZBFGYYEXUXCOF-UHFFFAOYSA-K
Synonym tris 2-carboxyethyl phosphine hydrochloride, tcep hcl, tcep hydrochloride, 3,3',3-phosphinetriyltripropanoic acid hydrochloride, tcep, unii-h49aam893k, tris carboxyethyl phosphine hydrochloride, tris-2-carboxyethyl phosphine hydrochloride, tris 2-carboxyethyl phosphine hcl, 3,3',3-phosphinetriyltripropanoicacidhydrochloride
PubChem CID 2734570
IUPAC Name 3-[bis(2-carboxyethyl)phosphanyl]propanoic acid;hydrochloride
SMILES [O-]C(=O)CCP(CCC([O-])=O)CCC([O-])=O
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAH51864AA
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Thermo Scientific Chemicals
H51864AA
5 mL
Each for $108.56
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AAH51864AC
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Thermo Scientific Chemicals
H51864AC
25 mL
Each for $420.14
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AAH51864AE
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Thermo Scientific Chemicals
H51864AE
100 mL
Each for $1,359.29
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Description

Description

Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.

Solubility
Miscible with water and methanol.

Notes
Air sensitive. Store in cool place. Incompatible with strong oxidizing agents
Specifications

Chemical Identifiers

51805-45-9
247.16
PZBFGYYEXUXCOF-UHFFFAOYSA-K
2734570
[O-]C(=O)CCP(CCC([O-])=O)CCC([O-])=O
C9H12O6P
MFCD00145469
tris 2-carboxyethyl phosphine hydrochloride, tcep hcl, tcep hydrochloride, 3,3',3-phosphinetriyltripropanoic acid hydrochloride, tcep, unii-h49aam893k, tris carboxyethyl phosphine hydrochloride, tris-2-carboxyethyl phosphine hydrochloride, tris 2-carboxyethyl phosphine hcl, 3,3',3-phosphinetriyltripropanoicacidhydrochloride
3-[bis(2-carboxyethyl)phosphanyl]propanoic acid;hydrochloride

Specifications

51805-45-9
(HO2CCH2CH2)3P·HCl
5 mL
tris 2-carboxyethyl phosphine hydrochloride, tcep hcl, tcep hydrochloride, 3,3',3-phosphinetriyltripropanoic acid hydrochloride, tcep, unii-h49aam893k, tris carboxyethyl phosphine hydrochloride, tris-2-carboxyethyl phosphine hydrochloride, tris 2-carboxyethyl phosphine hcl, 3,3',3-phosphinetriyltripropanoicacidhydrochloride
PZBFGYYEXUXCOF-UHFFFAOYSA-K
3-[bis(2-carboxyethyl)phosphanyl]propanoic acid;hydrochloride
2734570
95%
Tris(2-carboxyethyl)phosphine hydrochloride
C9H12O6P
MFCD00145469
UN3265
Miscible with water and methanol.
[O-]C(=O)CCP(CCC([O-])=O)CCC([O-])=O
247.16
286.65
0.5M soln. in water
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Safety and Handling

Safety and Handling

GHS H Statement
H314
Causes severe skin burns and eye damage.

P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

H314-H335

DOTInformation : Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.

TSCA : No

Recommended Storage : Ambient temperatures

SDS
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RUO – Research Use Only