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Trimethylsilyl cyanide, 97%

CAS: 7677-24-9 | C4H9NSi | 99.21 g/mol

$107.33 - $946.21

Chemical Identifiers

CAS 7677-24-9
Molecular Formula C4H9NSi
Molecular Weight (g/mol) 99.21
MDL Number MFCD00001765
InChI Key LEIMLDGFXIOXMT-UHFFFAOYSA-N
Synonym trimethylsilyl cyanide, cyanotrimethylsilane, trimethylsilanecarbonitrile, trimethylsilylcyanide, silanecarbonitrile, trimethyl, trimethylsilylnitrile, tmscn, trimethyl silane cyanide, trimethylsilylcarbonitrile, tms cyanide
PubChem CID 82115
IUPAC Name trimethylsilylformonitrile
SMILES C[Si](C)(C)C#N
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AAA1959806
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Thermo Scientific Chemicals
A1959806
5 g
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AAA1959814
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A1959814
25 g
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AAA1959822
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A1959822
100 g
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Description

Description

Trimethylsilyl Cyanide is used as a reagent in the preparation of optically active cyanohydrins. It is used in the derivatization of complex metabolite mixtures by GC-MS. It is employed in the preparation of Reissert compounds, which represent reactive polyamides. Further, it is used to convert pyridine-N-oxides into 2-cyanopyridine. It is also used as a cyanide source in an enantioselective organocatalytic Strecker-type reaction of aliphatic N,N-dialkylhydrazones. In addition to this, it is used as a reagent for the cyanosilylation of aldehydes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylsilyl Cyanide is used as a reagent in the preparation of optically active cyanohydrins. It is used in the derivatization of complex metabolite mixtures by GC-MS. It is employed in the preparation of Reissert compounds, which represent reactive polyamides. Further, it is used to convert pyridine-N-oxides into 2-cyanopyridine. It is also used as a cyanide source in an enantioselective organocatalytic Strecker-type reaction of aliphatic N,N-dialkylhydrazones. In addition to this, it is used as a reagent for the cyanosilylation of aldehydes.

Solubility
Miscible with organic solvents.

Notes
Moisture sensitive. Store in a cool place.Incompatible with water, strong oxidizing agents, strong reducing agents, strong acids and strong bases.
Specifications

Chemical Identifiers

7677-24-9
99.21
LEIMLDGFXIOXMT-UHFFFAOYSA-N
82115
C[Si](C)(C)C#N
C4H9NSi
MFCD00001765
trimethylsilyl cyanide, cyanotrimethylsilane, trimethylsilanecarbonitrile, trimethylsilylcyanide, silanecarbonitrile, trimethyl, trimethylsilylnitrile, tmscn, trimethyl silane cyanide, trimethylsilylcarbonitrile, tms cyanide
trimethylsilylformonitrile

Specifications

118°C to 119°C
7677-24-9
C4H9NSi
UN3383
1°C (33°F)
Miscible with organic solvents.
C[Si](C)(C)C#N
99.21
99.21
Almond-like
Moisture sensitive
Trimethylsilyl cyanide
11°C to 12°C
5 g
MFCD00001765
1737612
trimethylsilyl cyanide, cyanotrimethylsilane, trimethylsilanecarbonitrile, trimethylsilylcyanide, silanecarbonitrile, trimethyl, trimethylsilylnitrile, tmscn, trimethyl silane cyanide, trimethylsilylcarbonitrile, tms cyanide
LEIMLDGFXIOXMT-UHFFFAOYSA-N
trimethylsilylformonitrile
82115
97%
1.391
0.783
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Safety and Handling

Safety and Handling

GHS H Statement
H225-H300-H310-H330
Highly flammable liquid and vapour.
Fatal if swallowed.
Fatal in contact with skin.
Fatal if inhaled.

P210-P233-P235-P240-P241-P242-P243-P260-P262-P264b-P270-P271-P280-P284-P301+P310-P303+P361+P353-P304+P340-P310-P330-P363-P370+P378q-P501c

H225-H300+H310+H330

DOTInformation : Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TOXIC BY INHALATION LIQUID, FLAMMABLE, N.O.S.

EINECSNumber : 231-657-3

TSCA : Yes

Recommended Storage : Ambient temperatures

SDS
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RUO – Research Use Only