missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organic acids and derivatives
  6. Organic phosphonic acids and derivatives
  7. Trimethyl phosphonoacetate, 98%

Trimethyl phosphonoacetate, 98%

Catalog No. AAA1330114
Change view
missing translation for 'orderingAttributeHoverText'
Quantity:
100 g
25 g
500 g
Catalog No. Quantity
AAA1330114 25 g
AAA1330122 100 g
AAA1330136 500 g
3 options

Catalog No. AAA1330114

Supplier: Thermo Scientific Chemicals A1330114

Only null left

Description

CAS: 5927-18-4 | C5H11O5P | 182.112 g/mol

Trimethyl phosphonoacetate is used in the preparation of sarin A by intramolecular Mannich-type reactions. It is involved in the Horner-Wadsworth-Emmons olefination with aldehydes and ketones to give acrylic esters. It is also involved in oxa-Michael reactions, prenylation of oxindoles and heterocyclization reactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethyl phosphonoacetate is used in the preparation of sarin A by intramolecular Mannich-type reactions. It is involved in the Horner-Wadsworth-Emmons olefination with aldehydes and ketones to give acrylic esters. It is also involved in oxa-Michael reactions, prenylation of oxindoles and heterocyclization reactions.

Solubility
Slightly miscible with water.

Notes
Incompatible with strong oxidizing agents.

Chemical Identifiers

CAS 5927-18-4
Molecular Formula C5H11O5P
Molecular Weight (g/mol) 182.112
MDL Number MFCD00008452
InChI Key SIGOIUCRXKUEIG-UHFFFAOYSA-N
Synonym trimethyl phosphonoacetate, methyl 2-dimethoxyphosphoryl acetate, trimethyl phosphonacetate, trimethylacetyl phosphate, acetic acid, dimethoxyphosphinyl-, methyl ester, methyl-dimethoxyphosphoryl acetat, trimethyl phosphoroacetate, phosphonoacetic acid trimethyl ester, methyl dimethylphosphonoacetate, methyl dimethoxyphosphoryl acetate
PubChem CID 80029
IUPAC Name methyl 2-dimethoxyphosphorylacetate
SMILES COC(=O)CP(=O)(OC)OC

Specifications

Density 1.263
Boiling Point 119°C to 120°C (1 mmHg)
Flash Point 70°C (158°F)
Refractive Index 1.437
Quantity 25 g
Beilstein 1865177
Solubility Information Slightly miscible with water.
Formula Weight 182.11
Percent Purity 98%
Chemical Name or Material Trimethyl phosphonoacetate

Safety and Handling

Hazard Category Warning
Hazard Statement GHS H Statement
H315-H319-H335-H227
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Combustible liquid.
Precautionary Statement GHS P Statement
P210-P261-P280-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
EINECSNumber 227-663-0
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only