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Trimethyl orthoformate, 99%
CAS: 149-73-5 | C4H10O3 | 106.121 g/mol
Supplier: Thermo Scientific Chemicals A13760AP
Description
Trimethyl orthoformate is used as a protecting group for aldehydes in organic synthesis, as an additive in polyurethane coatings and as a dehydrating agent in the preparation of surface modified colloidal silica nanoparticles. It is also used as a chemical intermediate in the preparation of vitamin B1 and sulfa drugs. It acts as an effective solvent for thallium(III) nitrate-mediated oxidations. Furthermore. It is utilized for the synthesis of chromone from keto-hydroxy naphthol in the presence of trimethylamine.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsTrimethyl orthoformate is used as a protecting group for aldehydes in organic synthesis, as an additive in polyurethane coatings and as a dehydrating agent in the preparation of surface modified colloidal silica nanoparticles. It is also used as a chemical intermediate in the preparation of vitamin B1 and sulfa drugs. It acts as an effective solvent for thallium(III) nitrate-mediated oxidations. Furthermore. It is utilized for the synthesis of chromone from keto-hydroxy naphthol in the presence of trimethylamine.
Solubility
Miscible with ether, alcohol and benzene.
Notes
Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with acids and strong oxidizing agents.
Specifications
| Trimethyl orthoformate | |
| -53°C | |
| 101°C to 102°C | |
| C4H10O3 | |
| MFCD00008483 | |
| UN3272 | |
| Moisture sensitive | |
| trimethyl orthoformate, methyl orthoformate, methane, trimethoxy, orthoformic acid, trimethyl ester, orthoformic acid methyl ester, orthomravencan methylnaty, methoxymethylal, methylester kyseliny orthomravenci, unii-xam28819yj, orthoformic acid trimethyl ester | |
| PYOKUURKVVELLB-UHFFFAOYSA-N | |
| trimethoxymethane | |
| 9005 | |
| 99% |
| 149-73-5 | |
| 0.968 | |
| 15°C (59°F) | |
| 1.379 | |
| 500 mL | |
| 969215 | |
| 14,6884 | |
| Miscible with ether,alcohol and benzene. | |
| COC(OC)OC | |
| 106.121 | |
| 106.12 |
Chemical Identifiers
| 149-73-5 | |
| 106.121 | |
| PYOKUURKVVELLB-UHFFFAOYSA-N | |
| 9005 | |
| COC(OC)OC |
| C4H10O3 | |
| MFCD00008483 | |
| trimethyl orthoformate, methyl orthoformate, methane, trimethoxy, orthoformic acid, trimethyl ester, orthoformic acid methyl ester, orthomravencan methylnaty, methoxymethylal, methylester kyseliny orthomravenci, unii-xam28819yj, orthoformic acid trimethyl ester | |
| trimethoxymethane |
Safety and Handling
GHS H Statement
H225-H315-H319-H335
Highly flammable liquid and vapour.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P370+P378q-P501c
H225-H319-H335
DOTInformation : Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: ESTERS, N.O.S.
EINECSNumber : 205-745-7
RTECSNumber : RM6650000
TSCA : Yes
Recommended Storage : Ambient temperatures; Store under Nitrogen
RUO – Research Use Only