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Trimethyl orthoformate, 99%

Catalog No. aaa13760ae
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Quantity:
100 mL
2500 mL
500 mL
Catalog No. Quantity
AAA13760AE 100 mL
AAA13760AP 500 mL
AAA137600F 2500 mL
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Catalog No. AAA13760AE

Supplier: Thermo Scientific Chemicals A13760AE

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This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.

Description

CAS: 149-73-5 | C4H10O3 | 106.121 g/mol

Trimethyl orthoformate is used as a protecting group for aldehydes in organic synthesis, as an additive in polyurethane coatings and as a dehydrating agent in the preparation of surface modified colloidal silica nanoparticles. It is also used as a chemical intermediate in the preparation of vitamin B1 and sulfa drugs. It acts as an effective solvent for thallium(III) nitrate-mediated oxidations. Furthermore. It is utilized for the synthesis of chromone from keto-hydroxy naphthol in the presence of trimethylamine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethyl orthoformate is used as a protecting group for aldehydes in organic synthesis, as an additive in polyurethane coatings and as a dehydrating agent in the preparation of surface modified colloidal silica nanoparticles. It is also used as a chemical intermediate in the preparation of vitamin B1 and sulfa drugs. It acts as an effective solvent for thallium(III) nitrate-mediated oxidations. Furthermore. It is utilized for the synthesis of chromone from keto-hydroxy naphthol in the presence of trimethylamine.

Solubility
Miscible with ether, alcohol and benzene.

Notes
Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with acids and strong oxidizing agents.

Chemical Identifiers

CAS 149-73-5
Molecular Formula C4H10O3
Molecular Weight (g/mol) 106.121
MDL Number MFCD00008483
InChI Key PYOKUURKVVELLB-UHFFFAOYSA-N
Synonym trimethyl orthoformate, methyl orthoformate, methane, trimethoxy, orthoformic acid, trimethyl ester, orthoformic acid methyl ester, orthomravencan methylnaty, methoxymethylal, methylester kyseliny orthomravenci, unii-xam28819yj, orthoformic acid trimethyl ester
PubChem CID 9005
IUPAC Name trimethoxymethane
SMILES COC(OC)OC

Specifications

Melting Point -53°C
Density 0.968
Boiling Point 101°C to 102°C
Flash Point 15°C (59°F)
Refractive Index 1.379
Quantity 100 mL
UN Number UN3272
Beilstein 969215
Sensitivity Moisture sensitive
Merck Index 14,6884
Solubility Information Miscible with ether,alcohol and benzene.
Formula Weight 106.12
Percent Purity 99%
Chemical Name or Material Trimethyl orthoformate
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Safety and Handling

Hazard Category H225-H319-H335
Hazard Statement GHS H Statement
H225-H315-H319-H335
Highly flammable liquid and vapour.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P370+P378q-P501c
DOTInformation Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: ESTERS, N.O.S.
EINECSNumber 205-745-7
RTECSNumber RM6650000
TSCA Yes
Recommended Storage Ambient temperatures; Store under Nitrogen

RUO – Research Use Only