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Alfa Aesar™ Trifluoroacetic acid, biochemical grade, 99.5+%

Chemical Identifiers

Chemical Name or Material Trifluoroacetic acid
CAS 76-05-1
Purity Grade Biochemical Grade
Molecular Formula CF3CO2H
Formula Weight 114.02g/mol
MDL Number MFCD00004169
UN Number UN2699
Beilstein 742035
Merck Index 14,9681
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAA143650B

 
alfa aesar™
A14365-0B
1000g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAA1436518

 
alfa aesar™
A14365-18
50g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAA1436530

 
alfa aesar™
A14365-30
250g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Odor Pungent
Melting Point −15°C
Boiling Point 72° to 73°C
Quantity 1000g
Chemical Name or Material Trifluoroacetic acid
CAS 76-05-1
Purity Grade Biochemical Grade
Assay ≥99.5%
Molecular Formula CF3CO2H
Formula Weight 114.02g/mol
MDL Number MFCD00004169
UN Number UN2699
Beilstein 742035
Merck Index 14,9681
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H314-H332
Causes severe skin burns and eye damage.
Harmful if inhaled.
Health Hazard 3 GHS P Statement
P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
DOT Information Transport Hazard Class: 8; Packing Group: I; Proper Shipping Name: TRIFLUOROACETIC ACID
RTECS Number AJ9625000
TSCA TSCA

Applications
Used to cleave peptide blocking groupsThe combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

Solubility
Miscible with ether, acetone, ethanol, benzene, hexane and carbon tetrachloride.

Notes
Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.

Safety and Handling

Danger

GHS P Statement
P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H314-H332
Causes severe skin burns and eye damage.
Harmful if inhaled.