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Tetronic acid, 96%
Description
Tetronic acid is used as a precursor of a variety of substituted and ring-fused furans and butenolides. It is an acidic building block for heterocyclic compounds for medicinal applications. It is used for selective O-alkyaltion reactions involving cesium fluoride. It is also used to prepare 3H-furo[3,4-b]quinolin-1-one by reacting with 2-amino-benzaldehyde.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Tetronic acid is used as a precursor of a variety of substituted and ring-fused furans and butenolides. It is an acidic building block for heterocyclic compounds for medicinal applications. It is used for selective O-alkyaltion reactions involving cesium fluoride. It is also used to prepare 3H-furo[3,4-b]quinolin-1-one by reacting with 2-amino-benzaldehyde.
Solubility
Soluble in water, dimethyl sulfoxide, acetonitrile and alcohol.
Notes
Incompatible with strong oxidizing agents and strong alkalis (bases).
Tetronic acid is used as a precursor of a variety of substituted and ring-fused furans and butenolides. It is an acidic building block for heterocyclic compounds for medicinal applications. It is used for selective O-alkyaltion reactions involving cesium fluoride. It is also used to prepare 3H-furo[3,4-b]quinolin-1-one by reacting with 2-amino-benzaldehyde.
Solubility
Soluble in water, dimethyl sulfoxide, acetonitrile and alcohol.
Notes
Incompatible with strong oxidizing agents and strong alkalis (bases).
Specifications
Specifications
| Melting Point | ∽140°C (decomposition) |
| Assay Percent Range | 96% |
| Beilstein | 108442 |
| Synonym | tetronic acid, 2,4 3h,5h-furandione, furan-2,4 3h,5h-dione, tetrahydrofuran-2,4-dione, beta-tetronic acid, butanoic acid, 4-hydroxy-3-oxo-, .gamma.-lactone, tetronicacid, 2,4-furandione, tetrahydrofuran-3,5-dione, 3,5-dihydrofuran-2,4-dione |
| Solubility Information | Soluble in water,dimethyl sulfoxide,acetonitrile and alcohol. |
| IUPAC Name | 4-hydroxy-2,5-dihydrofuran-2-one |
| PubChem CID | 521261 |
| Formula Weight | 100.07 |
| Percent Purity | 96% |
| Quantity | 5 g |
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Safety and Handling
| Hazard Category | H315-H319-H335 |
| Hazard Statement | GHS H Statement H315-H319-H335 |
| Precautionary Statement | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c |
| EINECSNumber | 208-785-3 |
| TSCA | No |
| Recommended Storage | Ambient temperatures |
RUO – Research Use Only