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  7. tert-Butyldimethylchlorosilane, 97%

tert-Butyldimethylchlorosilane, 97%

Catalog No. AAA1306406
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100 g
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Catalog No. Quantity
AAA1306406 5 g
AAA1306414 25 g
AAA1306422 100 g
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Catalog No. AAA1306406

Supplier: Thermo Scientific Chemicals A1306406

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Description

CAS: 18162-48-6 | C6H15ClSi | 150.721 g/mol

tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

Solubility
Soluble in chloroform and ethyl acetate. Insoluble in water.

Notes
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.

Chemical Identifiers

CAS 18162-48-6
Molecular Formula C6H15ClSi
Molecular Weight (g/mol) 150.721
MDL Number MFCD00000501
InChI Key BCNZYOJHNLTNEZ-UHFFFAOYSA-N
Synonym tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride
PubChem CID 28928
ChEBI CHEBI:85071
IUPAC Name tert-butyl-chloro-dimethylsilane
SMILES CC(C)(C)[Si](C)(C)Cl

Specifications

Boiling Point 124°C to 126°C
Melting Point 86°C to 89°C
Quantity 5 g
Linear Formula (CH3)3CSi(CH3)2Cl
UN Number UN2925
Beilstein 505999
Flash Point 22°C (72°F)
Solubility Information Soluble in chloroform and ethyl acetate. Insoluble in water.
Formula Weight 150.73
Percent Purity 97%
Odor Pungent
Sensitivity Moisture sensitive
Density 0.81
Chemical Name or Material tert-Butyldimethylchlorosilane
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Safety and Handling

Hazard Category H228-H314-H335
Hazard Statement GHS H Statement
H228-H314-H318
Flammable solid.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Precautionary Statement P210-P240-P241-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation Hazard Class: 8; Packaging Group: I
EINECSNumber 242-042-4
RTECSNumber VV2000000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only