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  8. tert-Butyl carbazate, 98+%

tert-Butyl carbazate, 98+%

Catalog No. AAA1238314
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Catalog No. Quantity
AAA1238314 25 g
AAA1238322 100 g
AAA1238336 500 g
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Catalog No. AAA1238314

Supplier: Thermo Scientific Chemicals A1238314

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Description

CAS: 870-46-2 | C5H12N2O2 | 132.163 g/mol

tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.

Solubility
Soluble in ethanol and methanol.

Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.

Chemical Identifiers

CAS 870-46-2
Molecular Formula C5H12N2O2
Molecular Weight (g/mol) 132.163
MDL Number MFCD00007593
InChI Key DKACXUFSLUYRFU-UHFFFAOYSA-N
Synonym tert-butyl carbazate, tert-butyl hydrazinecarboxylate, t-butyl carbazate, hydrazinecarboxylic acid, 1,1-dimethylethyl ester, t-butylcarbazate, tert-butoxycarbonyl hydrazide, boc-hydrazide, boc-hydrazine, tert-butoxycarbonyl hydrazine, carbazic acid tert-butyl ester
PubChem CID 70091
IUPAC Name tert-butyl N-aminocarbamate
SMILES CC(C)(C)OC(=O)NN

Specifications

Melting Point 37°C to 41°C
Boiling Point 63°C to 65°C (0.1 mmHg)
Flash Point 91°C (195°F)
Quantity 25 g
UN Number UN1325
Beilstein 1756967
Sensitivity Moisture sensitive
Solubility Information Soluble in ethanol and methanol.
Formula Weight 132.16
Percent Purity ≥98%
Chemical Name or Material tert-Butyl carbazate
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Safety and Handling

Hazard Category H228-H301+H311-H315-H319-H335
Hazard Statement GHS H Statement
H228
Flammable solid.
Precautionary Statement P210-P240-P241-P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P361-P363-P370+P378q-P501c
DOTInformation Hazard Class: 4.1; Packaging Group: II
EINECSNumber 212-795-3
TSCA Yes
Recommended Storage Keep cold

RUO – Research Use Only