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  6. Thermo Scientific Chemicals Temsirolimus, 99+%

Thermo Scientific Chemicals Temsirolimus, 99+%

Numéro de catalogue. AAJ63654MF
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AAJ63654MF 50 mg
AAJ63654MC 100 mg
AAJ63654MB 25 mg
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Numéro de catalogue. AAJ63654MF Fournisseur Thermo Scientific Chemicals Code fournisseur J63654MF
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Description

A Rapamycin derivative with anti-cancer activity that inhibits mTOR | CAS: 162635-04-3 | C56H87NO16

Temsirolimus is used as a rapamycin derivative with anti-cancer activity that inhibits mTOR. Temsirolimus is an antiproliferative and antiangiogenic, the first-in-class mTOR inhibitor approved for the treatment of patients with advanced poor prognosis renal cell carcinoma.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Identifiants chimiques

CAS 162635-04-3
Molecular Formula C56H87NO16

Spécifications

Quantity 50 mg
Description White to Off-white
Content And Storage -30°C to -10°C
For Use With (Application) A Rapamycin derivative with anti-cancer activity that inhibits mTOR
Formula Weight 1030.29g/mol
Product Type Signal Transduction Reagent
Form Powder
MDL Number MFCD00934421
InChI Key CBPNZQVSJQDFBE-QYCDWSQESA-N
SMILES [H]C12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@]([H])(CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C(C)[C@H](C2)OC)[C@H](C)C[C@@H]1CC[C@@H](OC(=O)C(C)(CO)CO)[C@@H](C1)OC
IUPAC Name (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,18R,19R,21R,23S,30S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexyl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate
Molecular Weight (g/mol) 1030.30
Assay ≥99%
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Sécurité et manipulation

Recommended Storage Store at -20°C

RUO – Research Use Only