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Tocris Bioscience™ TAT-Gap19

Catalog No. 62271
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62271 1 mg
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Catalog No. 62271 Supplier Tocris Bioscience™ Supplier No. 6227/1*
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Description

Cx43 hemichannel blocker

TAT-Gap19 is a Cx43 hemichannel blocker (IC50 ~7 μM). No significant affinity for gap junctions or Panx1 channels. N-terminal transactivator of transcription (TAT) motif promotes membrane permeability and increases inhibitory effect of Gap19 (Cat. No. 5353). Active in vivo. Brain penetrant.

Specifications

Purity 95%
CAS 1507930-54-2
Content And Storage Store at −20°C
Molecular Weight (g/mol) 2703.28g/mol
Quantity 1 mg
Regulatory Status RUO - research use only
Sequence YGRKKRRQRRRKQIEIKKFK
Specific Reactivity Cx43 hemichannel blocker (IC50=7μM)

For Research Use Only