MilliporeSigma™ Supelco™ Supelclean™ Ultra 2400

This multi-bed solid phase extraction (SPE) cartridge was designed for the cleanup of extracts of difficult matrices such as dry commodities (tea, spices, coffee, etc.) prior to pesticide residue analysis, typically performed by GC/MSMS and LC/MS/MS. These types of samples can contain pigments and oils, and may not be sufficiently cleaned using a standard QuEChERS cleanup. The top bed consists of a mixture of PSA/C18 and a graphitized, spherical carbon. PSA removes acidic interferences, C18 retains some hydrophobic interferences, and carbon removes pigments. The variety of carbon used in this cartridge was engineered to remove sufficient pigmentation while allowing for better recoveries of compounds with planar structures. The bottom bed of the cartridge contains Z-Sep, which is a zirconia-coated silica. Z-Sep removes oily residues, and provides additional pigment removal.The cartridge can be used for cleanup of acetonitrile extracts to be analyzed by either GC or HPLC.