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  6. Thermo Scientific Chemicals Sulindac

Thermo Scientific Chemicals Sulindac

Catalog No. AAJ6177214
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AAJ6177206 5 g
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Catalog No. AAJ6177214 Supplier Thermo Scientific Chemicals Supplier No. J6177214
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Description

CAS: 38194-50-2 | C20H17FO3S, C20H17FO3S | 356.41 g/mol

Sulindac inhibits the NF-κB pathway. Sulindac is a non-steroidal anti-inflammatory drug. Sulindac reduces the level and activity of several cyclin-dependent kinases and induces apoptosis. It is an antitumor agent. Sulindac is an inhibitor of Cox-1 and Cox-2.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

A non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase-1 and induces apoptosis in HT-29 cells.

Chemical Identifiers

CAS 38194-50-2
Molecular Formula C20H17FO3S
Synonym cis-5-Fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]indene-3-acetic acid; MK-231

Specifications

Quantity 25 g
Description Yellow
Content And Storage -30°C to -10°C
For Use With (Application) A non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase-1 and induces apoptosis in HT-29 cells
Formula Weight 356.41g/mol
Melting Point 182°C to 185°C
Product Type Signal Transduction Reagent
Form Powder
InChI Key MLKXDPUZXIRXEP-MFOYZWKCNA-N
SMILES CC1=C(CC(O)=O)C2=CC(F)=CC=C2\C1=C/C1=CC=C(C=C1)S(C)=O
IUPAC Name 2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid
Molecular Weight (g/mol) 356.41
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Safety and Handling

EINECSNumber 253-819-2
Recommended Storage Store at -20°C

RUO – Research Use Only