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Invitrogen™ Rat VAMP2 (aa 1-18) Synthetic Peptide

Catalog No. PEP101
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50 μg
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Catalog No. Quantity
PEP101 50 μg
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Catalog No. PEP101 Supplier Invitrogen™ Supplier No. PEP101
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Description

Synthetic Peptide

Rat VAMP-2 (residues 1-18) Synthetic Peptide, PEP-101, from Invitrogen.

The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer's disease, VAMP levels of all isoforms appear to be significantly lowered. It is suggested that VAMP-2 is a resident protein of the insulin-sensitive glucose transporter type 4 (GLUT4) compartment and that it is required for GLUT4 vesicle incorporation into the cell surface in response to insulin.

Specifications

Gene ID (Entrez) 24803
Species Rat
Purification Method purified
Accession Number P63045
Common Name Rat VAMP2 (aa 1-18)
Concentration 0.5 mg/mL
Content And Storage -20°C. Avoid freeze-thaw cycles.
Description Synthetic Peptide
Format Lyophilized
Formulation peptide with no preservative
For Use With (Application) Control
Gene Symbol Vamp2
Lyophilized Lyophilized
Preservative No preservative
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Sequence M(1)-S-A-T-A-A-T-V-P-P-A-A-P-A-G-E-G-G(18)
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