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Invitrogen™ Rat RAB3d (aa 1-18) Synthetic Peptide

Catalog No. PEP144
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50 μg
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Catalog No. Quantity
PEP144 50 μg
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Catalog No. PEP144 Supplier Invitrogen™ Supplier No. PEP144

Description

Synthetic Peptide

PEP-144 is an 18 amino acid synthetic peptide whose sequence corresponds to residues 1-18 from rat rab 3D. The sequence of this peptide is (amino to carboxy terminus): M (1)-A-S-A-S-E-P-P-A-S-P-R-D-A-A-D-Q-N (18) This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat rab 3D, catalog # PA1-773. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions. Reconstitute with 0.1 mL of distilled water.

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 rab proteins that have been described in mammals. Rab 3D has been shown to be present, in part, in the tongue, pancreas, and liver.

Specifications

Gene ID (Entrez) 140665
Species Rat
Purification Method purified
Accession Number Q63942
Common Name RAB3d
Concentration 0.5 mg/mL
Content And Storage -20°C. Avoid freeze-thaw cycles.
Description Synthetic Peptide
Format Lyophilized
Formulation Peptide with no preservative
For Use With (Application) Control
Gene Alias C130057E11Rik; D2-2; glioblastoma overexpressed; GOV; GTP-binding protein Rab-3D; RAB16; Rab3d; Rab3D upregulated with myeloid differentiation; RAB3D, member RAS oncogene family; RAD3D; Ras-related protein Rab-3D
Gene Symbol Rab3d
Lyophilized Yes
Preservative No preservative
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
Sequence M(1)-A-S-A-S-E-P-P-A-S-P-R-D-A-A-D-Q-N(18)
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