missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Biochemical Reagents
  4. Peptides
  5. PEP064

Invitrogen™ Rat AANAT (aa 24-33) Synthetic Peptide

Catalog No. PEP064
Change view
Click to view available options
Quantity:
50 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PEP064 50 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PEP064 Supplier Invitrogen™ Supplier No. PEP064

Description

Synthetic Peptide

PEP-064 is a 10 amino acid synthetic phospho-peptide whose sequence corresponds to residues 24-33 of rat AA-NAT. The sequence of this peptide is (amino to carboxy terminus): C24-Q-R-R-H-T (P)-L-P-A-S33 This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and Phospho-Thr29 AA-NAT, catalog # PA1-761. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions. Reconstitute with 0.1 mL of distilled water.

Arylalkylamine N-Acetyltransferase (AANAT) is the penultimate enzyme is melatonin synthesis. Hormonal melatonin has been implicated in sleep and circadian clock function. Large changes in the abundance of AANAT are believed to be responsible for the large day/night rhythms in melatonin synthesis in the pineal gland and retina. Most research shows that AANAT activity is regulated by controlling the steady-state levels of the protein. Recent research, however, suggests that another mechanism may also play a role in controlling melatonin production without altering AANAT protein and activity. This mechanism may explain the sudden physiological increase in circulating melatonin observed at the onset of the dark period in humans.

Specifications

Gene ID (Entrez) 25120
Species Rat
Purification Method purified
Accession Number Q64666
Common Name AANAT
Concentration 0.5 mg/mL
Content And Storage -20°C. Avoid freeze-thaw cycles.
Description Synthetic Peptide
Format Lyophilized
Formulation Peptide with no preservative
For Use With (Application) Control
Gene Alias Aanat; AA-NAT; Aralkylamine N-acetyltransferase; arylakylamine N-acetyltransferase; Arylalkylamine N - acetyltransferase (Serotonin N - acetyltransferase); arylalkylamine N-acetyltransferase; DSPS; Nat-2; Nat4; Seretonin N-acetyltransferase; serotonin acetylase; Serotonin N-acetyltransferase; SNAT
Gene Symbol Aanat
Lyophilized Yes
Preservative No preservative
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
Sequence C24 - Q - R - R - H - T(P) - L - P - A - S33
Show More Show Less