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Thermo Scientific™ POROS™ GoPure™ AAVX Column
Description
POROS GoPure AAVX chromatography columns are ready-to-use and designed specifically for use in clinical and commercial manufacturing. POROS GoPure AAVX columns are prepared and packed in an ISO Class 7 environment where all product contact materials meet USP <88> Class VI standards. Each column is accompanied by column qualification documentation including bioburden and endotoxin. Packed with POROS™ CaptureSelect™ AAVX affinity resin, POROS GoPure AAVX columns offer high specificity and capacity for a broad range of AAV viral vector serotypes over a wide range of flow rates.
- Pressure rating (bar/psi): 4/58
- Operating temperature: 2°C to 30°C
- Bed support size: 12 μm
- Inlet/outlet internal diameter: 2.00 mm (2.5 cm), 3.45 mm (5 cm), 4.57 mm (8 cm), 6.35 mm (10 cm)
- Inlet/outlet port connections: 3/4 inch mini tri-clamps
- Includes a 30 mL resin side sample for incoming QC
Features of POROS CaptureSelect AAVX resin include one-step AAV purification from crude material with high purity, with high specificity and capacity, improving yield by reducing process steps. Free of animal-origin components, the CaptureSelect AAVX ligand is a 12 to 15 kDa single-domain antibody fragment produced in the yeast Saccharomyces cerevisiae.
Specifications
Specifications
| Type | Chromatography Column |
| Diameter (Metric) Inner | 2.5 cm |
| Length (English) | 2 in. |
| Quantity | 1 Ea. |
| Pore Size | Not Applicable |
| Column Capacity | 25 mL |
| Length (Metric) | 5 cm |
For research and development use and further manufacturing in support of FDA-regulated end uses. Not for diagnostic use or direct administration to human or animals.