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Norfloxacin

Catalog No. p-7042473
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AAJ6265203 1 g
AAJ6265206 5 g
AAJ6265214 25 g
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Catalog No. AAJ6265203 Supplier Thermo Scientific Chemicals Supplier No. J6265203
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Description

A synthetic fluoroquinolone antibiotic | CAS: 70458-96-7 | C16H18FN3O3 | 319.336 g/mol

It finds it application as a fluorinated quinolone antibacterial. It is clinically used to treat urinary tract infections and prostatitis. In neutrophils from cirrhotic subjects, norfloxacin increases expression of IL-10 and heme oxygenase 1 (HO-1) and decreases expression of pro-inflammatory cytokines. Additionally, when complexed with gold(III), norfloxacin binds DNA and inhibits cellular proliferation in several cancer cell lines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in acetic acid. Also soluble in acetone or cloroform. Slightly soluble in water

Notes
Store away from heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Keep it refrigerated.

Chemical Identifiers

CAS 70458-96-7
Molecular Formula C16H18FN3O3
Molecular Weight (g/mol) 319.336
MDL Number MFCD00079532
InChI Key OGJPXUAPXNRGGI-UHFFFAOYSA-N
Synonym Baccidal; Sebercim
PubChem CID 4539
ChEBI CHEBI:100246
IUPAC Name 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
SMILES CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O

Specifications

Type Norfloxacin
Physical Form Powder
Melting Point 220°C to 221°C
Color White to Yellow
Quantity 1 g
Merck Index 14,6700
Solubility Information Soluble in acetic acid; Also soluble in acetone or cloroform; Slightly soluble in water
Formula Weight 319.33
Chemical Name or Material Norfloxacin

Safety and Handling

EINECSNumber 274-614-4
RTECSNumber VB5005000
TSCA No
Recommended Storage Keep cold

RUO – Research Use Only