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Norfloxacin
A synthetic fluoroquinolone antibiotic | CAS: 70458-96-7 | C16H18FN3O3 | 319.336 g/mol
$50.84 - $353.05
Chemical Identifiers
| CAS | 70458-96-7 |
|---|---|
| Molecular Formula | C16H18FN3O3 |
| Molecular Weight (g/mol) | 319.336 |
| MDL Number | MFCD00079532 |
| InChI Key | OGJPXUAPXNRGGI-UHFFFAOYSA-N |
| Synonym | Baccidal; Sebercim |
| PubChem CID | 4539 |
| ChEBI | CHEBI:100246 |
| IUPAC Name | 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid |
| SMILES | CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ6265203
|
Thermo Scientific Chemicals
J6265203 |
1 g |
Each for $50.84
|
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AAJ6265206
|
Thermo Scientific Chemicals
J6265206 |
5 g |
Each for $121.45
|
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|
AAJ6265214
|
Thermo Scientific Chemicals
J6265214 |
25 g |
Each for $353.05
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Description
It finds it application as a fluorinated quinolone antibacterial. It is clinically used to treat urinary tract infections and prostatitis. In neutrophils from cirrhotic subjects, norfloxacin increases expression of IL-10 and heme oxygenase 1 (HO-1) and decreases expression of pro-inflammatory cytokines. Additionally, when complexed with gold(III), norfloxacin binds DNA and inhibits cellular proliferation in several cancer cell lines.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
SolubilitySoluble in acetic acid. Also soluble in acetone or cloroform. Slightly soluble in water
Notes
Store away from heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Keep it refrigerated.
Chemical Identifiers
| 70458-96-7 | |
| 319.336 | |
| OGJPXUAPXNRGGI-UHFFFAOYSA-N | |
| 4539 | |
| 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid |
| C16H18FN3O3 | |
| MFCD00079532 | |
| Baccidal; Sebercim | |
| CHEBI:100246 | |
| CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O |
Specifications
| Norfloxacin | |
| 70458-96-7 | |
| White to Yellow | |
| C16H18FN3O3 | |
| 14,6700 | |
| Soluble in acetic acid; Also soluble in acetone or cloroform; Slightly soluble in water | |
| CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O | |
| 319.336 | |
| CHEBI:100246 | |
| Norfloxacin |
| Powder | |
| 220°C to 221°C | |
| 1 g | |
| MFCD00079532 | |
| Baccidal; Sebercim | |
| OGJPXUAPXNRGGI-UHFFFAOYSA-N | |
| 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid | |
| 4539 | |
| 319.33 |
Safety and Handling
EINECSNumber : 274-614-4
RTECSNumber : VB5005000
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only