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Nitro Blue Tetrazolium chloride, 98+%
Intense blue dye used in histochemistry determinations | CAS: 298-83-9 | C40H30Cl2N10O6 | 817.644 g/mol
Supplier: Thermo Scientific Chemicals J6023006
Description
Intense blue dye used in histochemistry determinations.Nitro Blue Tetrazolium chloride is used to confirm diagnosis of chronic granulomatous disease. It is a microscopic stain, which is used to detect dehydrogenases and alkaline phosphatase. It acts as an NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase. Further, it is used in immunology for detection of alkaline phosphatase. In addition to this, it acts as an oxidant.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsIntense blue dye used in histochemistry determinations.Nitro Blue Tetrazolium chloride is used to confirm diagnosis of chronic granulomatous disease. It is a microscopic stain, which is used to detect dehydrogenases and alkaline phosphatase. It acts as an NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase. Further, it is used in immunology for detection of alkaline phosphatase. In addition to this, it acts as an oxidant.
Solubility
Soluble in water, ethanol and methanol.
Notes
Light sensitive. Store in a cool place. Incompatible with strong oxidizing agents.
Specifications
| Nitro Blue Tetrazolium chloride | |
| 298-83-9 | |
| MFCD00012159 | |
| Nitro BT; Nitrotetrazolium Blue chloride | |
| FSVCQIDHPKZJSO-UHFFFAOYSA-L | |
| 2-[2-methoxy-4-[3-methoxy-4-[3-(4-nitrophenyl)-5-phenyltetrazol-2-ium-2-yl]phenyl]phenyl]-3-(4-nitrophenyl)-5-phenyltetrazol-2-ium;dichloride | |
| 9281 | |
| 817.65 | |
| Light sensitive | |
| 5 g |
| ∼190°C (decomposition) | |
| C40H30Cl2N10O6 | |
| 4115923 | |
| Soluble in water,ethanol and methanol. | |
| COC1=C(C=CC(=C1)C2=CC(=C(C=C2)[N+]3=NC(=NN3C4=CC=C(C=C4)[N+](=O)[O-])C5=CC=CC=C5)OC)[N+]6=NC(=NN6C7=CC=C(C=C7)[N+](=O)[O-])C8=CC=CC=C8.[Cl-].[Cl-] | |
| 817.644 | |
| CHEBI:9505 | |
| 99% | |
| Yellow | |
| Crystalline Powder |
Chemical Identifiers
| 298-83-9 | |
| 817.644 | |
| FSVCQIDHPKZJSO-UHFFFAOYSA-L | |
| 9281 | |
| 2-[2-methoxy-4-[3-methoxy-4-[3-(4-nitrophenyl)-5-phenyltetrazol-2-ium-2-yl]phenyl]phenyl]-3-(4-nitrophenyl)-5-phenyltetrazol-2-ium;dichloride |
| C40H30Cl2N10O6 | |
| MFCD00012159 | |
| Nitro BT; Nitrotetrazolium Blue chloride | |
| CHEBI:9505 | |
| COC1=C(C=CC(=C1)C2=CC(=C(C=C2)[N+]3=NC(=NN3C4=CC=C(C=C4)[N+](=O)[O-])C5=CC=CC=C5)OC)[N+]6=NC(=NN6C7=CC=C(C=C7)[N+](=O)[O-])C8=CC=CC=C8.[Cl-].[Cl-] |
Safety and Handling
GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302-H315-H319-H335
EINECSNumber : 206-067-4
RTECSNumber : XF8045000
TSCA : Yes
Recommended Storage : Keep cold
RUO – Research Use Only