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  7. Nifedipine, 98%

Nifedipine, 98%

Numéro de catalogue. p-7042517
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Numéro de catalogue. Quantity
AAJ6281106 5 g
AAJ6281114 25 g
AAJ6281122 100 g
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Numéro de catalogue. AAJ6281106 Fournisseur Thermo Scientific Chemicals Code fournisseur J6281106
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Description

L-type calcium channel blocker; induces apoptosis in human glioblastoma cells | CAS: 21829-25-4 | C17H18N2O6 | 346.34 g/mol

L-type calcium channel blocker; induces apoptosis in human glioblastoma cells.Nifedipine is a dihydropyridine calcium channel blocker used as L-type calcium channel blocker, antianginal and an antihypertensive . It induces apoptosis in human glioblastoma cells. It is used as a coronary vasodilator in the treatment of cardiac and circulatory disorders. Further, it is used in high-altitude medicine to treat high altitude pulmonary edema, hypertension and chronic stable angina. In addition, it is frequently used as a tocolytic agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
L-type calcium channel blocker; induces apoptosis in human glioblastoma cells.Nifedipine is a dihydropyridine calcium channel blocker used as L-type calcium channel blocker, antianginal and an antihypertensive . It induces apoptosis in human glioblastoma cells. It is used as a coronary vasodilator in the treatment of cardiac and circulatory disorders. Further, it is used in high-altitude medicine to treat high altitude pulmonary edema, hypertension and chronic stable angina. In addition, it is frequently used as a tocolytic agent.

Solubility
Soluble in acetone, methylene chloride, chloroform, ethyl acetate, dimethyl sulfoxide and methanol. Sparingly soluble in ethanol. Insoluble in water.

Notes
Light sensitive. Store in a cool place. Incompatible with strong acids, strong oxidizing agents, caustics, aliphatic amines, amides, diethylamine, potassium hydride and potassium hydroxide.

Identifiants chimiques

CAS 21829-25-4
Molecular Formula C17H18N2O6
Molecular Weight (g/mol) 346.34
MDL Number MFCD00057326
InChI Key HYIMSNHJOBLJNT-UHFFFAOYSA-N
Synonym nifedipine, procardia, adalat, procardia xl, adalat cc, cordipin, corinfar, fenihidine, citilat, oxcord
PubChem CID 4485
ChEBI CHEBI:7565
IUPAC Name 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
SMILES COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC

Spécifications

Melting Point 171°C to 175°C
Color White to Yellow
Quantity 5 g
Merck Index 14,6528
Solubility Information Soluble in acetone,methylene chloride,chloroform,ethyl acetate,dimethyl sulfoxide and methanol. Sparingly soluble in ethanol. Insoluble in water.
Formula Weight 346.33
Percent Purity 98%
Physical Form Powder
Chemical Name or Material Nifedipine

Sécurité et manipulation

Hazard Category H302
Hazard Statement GHS H Statement
H302
Harmful if swallowed.
Precautionary Statement P264b-P270-P301+P312-P330-P501c
EINECSNumber 244-598-3
RTECSNumber US7975000
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only