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  8. Nicotinamide, 99%

Nicotinamide, 99%

Catalog No. p-7022962
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AAA1597022 100 g
AAA1597030 250 g
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Catalog No. AAA1597022 Supplier Thermo Scientific Chemicals Supplier No. A1597022
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Description

CAS: 98-92-0 | C6H6N2O | 122.127 g/mol

Nicotinamide is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). It may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule. It is an amide derivative of vitamin B3 and a PARP inhibitor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Nicotinamide is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). It may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule. It is an amide derivative of vitamin B3 and a PARP inhibitor.

Solubility
Soluble in water, ethanol , glycerol, DMSO , methanol, butanol and chloroform. Slightly soluble in ether.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

Chemical Identifiers

CAS 98-92-0
Molecular Formula C6H6N2O
Molecular Weight (g/mol) 122.127
MDL Number MFCD00006395
InChI Key DFPAKSUCGFBDDF-UHFFFAOYSA-N
Synonym nicotinamide, niacinamide, 3-pyridinecarboxamide, vitamin pp, nicotinic acid amide, papulex, aminicotin, amixicotyn, nicobion, nicotylamide
PubChem CID 936
ChEBI CHEBI:17154
IUPAC Name pyridine-3-carboxamide
SMILES C1=CC(=CN=C1)C(=O)N

Specifications

Melting Point 128°C to 132°C
Flash Point 182°C (360°F)
Odor Odorless
Assay Percent Range 99%
Quantity 100 g
Beilstein 383619
Merck Index 14,6523
Formula Weight 122.13
Percent Purity 99%
Chemical Name or Material Nicotinamide

Safety and Handling

Hazard Category Warning
Hazard Statement GHS H Statement
H319
Causes serious eye irritation.
Precautionary Statement GHS P Statement
P280-P264-P305+P351+P338-P337+P313
Wear protective gloves/protective clothing/eye protection/face protection.
Wash thoroughly after handling.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF eye irritation persists: Get medical advice/attention.
RTECSNumber QS3675000
TSCA TSCA

RUO – Research Use Only