Thermo Scientific™ NanoDrop Ultra and Qubit 4 Bundle

Accuracy and Sensitivity:

• NanoDrop Ultra: Provides quick and easy quantification of nucleic acids and proteins directly from a small sample volume without the need for reagents. However, it may be less sensitive for low-concentration samples.
• Qubit 4: Uses fluorescent dyes specific to the target molecule, offering high sensitivity and accuracy for low-concentration samples.

Complementary Data:

• NanoDrop Ultra: Offers absorbance-based quantification, which is useful for a broad range of concentrations but in most cases required the sample to be purified. Acclaro contamination alerts provide the user with information on possible contaminats in the sample.
• Qubit 4: Provides fluorescence-based quantification, which is less affected by contaminants and more specific for the target molecule.

Verification:

• Using both instruments can help verify results. If the NanoDrop and Qubit measurements agree, it increases confidence in the data.
• Discrepancies might indicate the presence of contaminants or other issues that need to be addressed.

Efficiency:

• Combining both tools allows researchers to quickly screen samples with NanoDrop Ultra and then perform more accurate quantification on selected samples using Qubit 4.

Broader Application:

• NanoDrop Ultra: Suitable for routine measurements and quick checks.
• Qubit 4: Ideal for precise quantification needed in downstream applications like qPCR, sequencing, or other sensitive assays.