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  7. Naloxone Hydrocloride, MP Biomedicals™

Naloxone Hydrocloride, MP Biomedicals™

Catalog No. p-7139870
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Quantity:
1 g
250 mg
Catalog No. Quantity
MP219024583 250 mg
MP219024591 1 g
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Catalog No. MP219024583

Supplier: MP Biomedicals Inc 0219024583

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Description

Naloxone Hydrocloride Off-white Crystalline Powder

  • The role of naloxone (1μM) and other opioids on apoptosis in several human cancer cell lines has been probed. Naloxone (10-100μM) has been used to study proliferation and neurogenesis in cultured rat adult hippocampal progenitors.
  • Naloxone has also been utilized to modulate the NMDA receptor activation capability of theμ-opioid receptor agonist DAMGO. It displaces morphine and other opiate agonists from the opiate receptor.
  • It is more potent than Nalorphine and is also an effective antagonist for mixed agonist-antagonist drugs such as pentazorcine. Naloxone has no respiratory depressant activity.

Chemical Identifiers

CAS 357-08-4
Molecular Formula C19H22ClNO4
Molecular Weight (g/mol) 363.84
InChI Key RGPDIGOSVORSAK-STHHAXOLSA-N
Synonym Narcan, EN-1530, (5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one hydrochloride, 17-allyl-4,5α- epoxy-3,14-dihydroxymorphinan-6-one hydrochloride

Specifications

Melting Point 129.0°C to 129.2°C (literature)
Color Off-white
Quantity 250 mg
Beilstein 6260807
Solubility Information Soluble in water (50mg/mL - clear, colorless to faint yellow solution), ethanol (3.3mg/mL), or methanol (50mg/mL - clear, colorless solution).
Physical Form Crystalline Powder

Safety and Handling

RTECSNumber QD2275000
storageNote1 Store at +4°C, Store Desiccated.