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  7. Naloxone hydrochloride, 98%

Naloxone hydrochloride, 98%

Catalog No. p-7057380
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Quantity:
1 g
Catalog No. Quantity
AAJ6001303 1 g
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Catalog No. AAJ6001303

Supplier: Thermo Scientific Chemicals J6001303

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Description

Naloxone hydrochloride, CAS # 357-08-4, is involved in the blockade of the mu-opioid receptor and removal of other compounds from the receptor site. | CAS: 357-08-4 | C19H22ClNO4 | 363.838 g/mol

A specific opiate antagonist. Blocks the action of sigma-agonists at opioid sites.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Naloxone hydrochloride the hydrochloride salt of the anti-opioid naloxone

Application

  • Naloxone is a fast-acting inverse agonist of the mu-opioid receptor that can be used to competitively inhibit the binding of opioid compounds

Chemical Identifiers

CAS 357-08-4
Molecular Formula C19H22ClNO4
Molecular Weight (g/mol) 363.838
MDL Number MFCD00069322
InChI Key RGPDIGOSVORSAK-STHHAXOLSA-N
Synonym naloxone hydrochloride, naloxone hcl, narcan, evzio, unii-f850569pqr, nalonee, 17-allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, narcan tn, naloxonehydrochloride
PubChem CID 5464092
IUPAC Name (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
SMILES C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl

Specifications

Melting Point 200°C to 205°C
Color White
Quantity 1 g
Merck Index 14,6362
Solubility Information Soluble in water (73mg/ml),ethanol (3.3mg/ml),methanol (50mg/ml) and dimethyl sulfoxide (73mg/ml). Insoluble in ether
Formula Weight 363.84
Percent Purity 98%
Physical Form Crystalline Powder
Chemical Name or Material Naloxone hydrochloride

Safety and Handling

Hazard Category H302-H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber 206-611-0
RTECSNumber QD2275000
TSCA No
storageNote1 2° to 8°C
Recommended Storage Keep cold

RUO – Research Use Only