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N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS

Catalog No. AA4393946
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100 g
25 g
5 g
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Catalog No. Quantity
AA4393946 5 x 1 g
AA4393906 5 g
AA4393914 25 g
AA4393922 100 g
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Catalog No. AA4393946

Supplier: Thermo Scientific Chemicals 04393946

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CAS: 25561-30-2 | C8H18F3NOSi2 | 257.403 g/mol

N,O-Bis(trimethylsilyl)trifluoroacetamide is used as a derivatization reagent for gas chromatography and mass-spectrometry analysis of phenolic acids in fruits. It is also used as a reactant in the preparation of pyrimidinone ribosides and analogs which shows anti-tumor properties. It plays as an important role as a reagent for the regioselective desulfation of polysaccharide sulfates. Furthermore, it is used to prepare trimethylsilyl ethers of carbohydrates and alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

  • Ampouled under argon

Chemical Identifiers

CAS 25561-30-2
Molecular Formula C8H18F3NOSi2
Molecular Weight (g/mol) 257.403
MDL Number MFCD00008269
InChI Key XCOBLONWWXQEBS-GHXNOFRVSA-N
Synonym bstfa, n,o-bis trimethylsilyl trifluoroacetamide, acetamide, 2,2,2-trifluoro-o,n-bis trimethylsilyl, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl acetimidate, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl ethanimidate, trimethylsilyl 1z-2,2,2-trifluoro-n-z-trimethylsilyl ethanimidoate #, n,o-bis trimethylsilyl trifluoroacetamide bstfa, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl ethanecarboximidate
PubChem CID 9601896
IUPAC Name trimethylsilyl (1Z)-2,2,2-trifluoro-N-trimethylsilylethanimidate
SMILES C[Si](C)(C)N=C(C(F)(F)F)O[Si](C)(C)C

Specifications

Melting Point -10°C
Color Colorless to Yellow
Density 0.97 g/mL
Boiling Point 145°C to 147°C
Flash Point 23°C (73°F)
Packaging Ampule
Refractive Index 1.384
Quantity 5 x 1 g
UN Number UN2924
Beilstein 3607620
Sensitivity Moisture sensitive
Solubility Information Miscible with chloroform.
Formula Weight 257.4
Physical Form Liquid
Chemical Name or Material N,O-Bis (trimethylsilyl)trifluoroacetamide, With 1% TMCS
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Hazard Category H226-H314
Hazard Statement GHS H Statement
H314-H226
Causes severe skin burns and eye damage.
Flammable liquid and vapor.
Precautionary Statement P210-P233-P240-P241-P242-P243-P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, CORROSIVE, N.O.S.
EINECSNumber 247-103-9
TSCA Yes
storageNote1
  • Ampouled under argon
Recommended Storage Keep cold; Store under Nitrogen

RUO – Research Use Only