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N,N'-Disuccinimidyl carbonate, tech. 85%, remainder N-Hydroxysuccinimide
CAS: 74124-79-1 | C9H8N2O7 | 256.17 g/mol
Supplier: Thermo Scientific Chemicals H2662906
Description
N,N'-Disuccinimidyl carbonate is used to prepare cleavable linker succinimide vinylsufonylethyl carbonate for thiol modified-DNA. It serves as a reagent for the synthesis of carbamates. Further, it is used as a coupling reagent as well as in the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate and coupling of ligand to proteins.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsN,N′-Disuccinimidyl carbonate is used to prepare cleavable linker succinimide vinylsufonylethyl carbonate for thiol modified-DNA. It serves as a reagent for the synthesis of carbamates. Further, it is used as a coupling reagent as well as in the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate and coupling of ligand to proteins.
Solubility
Soluble in dimethyl sulfoxide, hot pyridine, acetonitrile and most organic solvents. Insoluble in water.
Notes
Moisture sensitive. Store in a cool place. Incompatible with strong acids and oxidizing agents.
Specifications
| N,N'-Disuccinimidyl carbonate | |
| 190°C (decomposition) | |
| C9H8N2O7 | |
| 5 g | |
| Hygroscopic | |
| Soluble in dimethyl sulfoxide,hot pyridine,acetonitrile and most organic solvents. Insoluble in water. | |
| C1CC(=O)N(C1=O)OC(=O)ON2C(=O)CCC2=O | |
| 256.17 | |
| 256.17 | |
| Technical |
| 74124-79-1 | |
| remainder N-Hydroxysuccinimide | |
| MFCD00009767 | |
| 1499137 | |
| n,n'-disuccinimidyl carbonate, bis 2,5-dioxopyrrolidin-1-yl carbonate, n,n'-disuccinimidylcarbonate, di succinimido carbonate, disuccinimidyl carbonate, di n-succinimidyl carbonate, n,n-disuccinimidyl carbonate, dsc, disuccinimido carbonate, pubchem12700 | |
| PFYXSUNOLOJMDX-UHFFFAOYSA-N | |
| bis(2,5-dioxopyrrolidin-1-yl) carbonate | |
| 676246 | |
| 85% |
Chemical Identifiers
| 74124-79-1 | |
| 256.17 | |
| PFYXSUNOLOJMDX-UHFFFAOYSA-N | |
| 676246 | |
| C1CC(=O)N(C1=O)OC(=O)ON2C(=O)CCC2=O |
| C9H8N2O7 | |
| MFCD00009767 | |
| n,n'-disuccinimidyl carbonate, bis 2,5-dioxopyrrolidin-1-yl carbonate, n,n'-disuccinimidylcarbonate, di succinimido carbonate, disuccinimidyl carbonate, di n-succinimidyl carbonate, n,n-disuccinimidyl carbonate, dsc, disuccinimido carbonate, pubchem12700 | |
| bis(2,5-dioxopyrrolidin-1-yl) carbonate |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
H315-H319-H335
EINECSNumber : 277-730-3
TSCA : No
Recommended Storage : Keep cold; Store under Nitrogen
RUO – Research Use Only