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N-Hydroxysulfosuccinimide sodium salt, 97%

Catalog No. p-7035089
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250 mg
1 g
5 g
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Catalog No. Quantity
AAH52795MD 250 mg
AAH5279503 1 g
AAH5279506 5 g
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Catalog No. AAH52795MD Supplier Thermo Scientific Chemicals Supplier No. H52795MD
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Description

CAS: 106627-54-7 | C4H4NNaO6S | 217.127 g/mol

N-Hydroxysulfosuccinimide sodium salt is used as crosslinking agents for preparing hydrophilic active esters. It is also used to activate carboxylic acids to the more reactive succinimidyl esters for coupling, biotinylation and conjugation with fluorophores. Further, it acts as a hydrophilic ligand and also used in covalently binding proteins to carboxyl containing beads, resins, other nanoparticles. It is involved in the conversion of carboxyl groups to primary amine-reactive sulfo-NHS esters.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Hydroxysulfosuccinimide sodium salt is used as crosslinking agents for preparing hydrophilic active esters. It is also used to activate carboxylic acids to the more reactive succinimidyl esters for coupling, biotinylation and conjugation with fluorophores. Further, it acts as a hydrophilic ligand and also used in covalently binding proteins to carboxyl containing beads, resins, other nanoparticles. It is involved in the conversion of carboxyl groups to primary amine-reactive sulfo-NHS esters.

Solubility
Soluble in methanol and water.

Notes
Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.

Chemical Identifiers

CAS 106627-54-7
Molecular Formula C4H4NNaO6S
Molecular Weight (g/mol) 217.127
MDL Number MFCD00043100
InChI Key RPENMORRBUTCPR-UHFFFAOYSA-M
Synonym n-hydroxysulfosuccinimide sodium salt, sulfo-nhs, sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate, n-hydroxysulfosuccinimidesodiumsalt, 3-pyrrolidinesulfonic acid, 1-hydroxy-2,5-dioxo-, monosodium salt, sodium 1-hydroxy-2,5-dioxo-pyrrolidine-3-sulfonate, n-hydroxusulfosuccinimide sodium, n-hydroxy-2-sodiosulfo succinimide, n-hydroxysulfosuccinimide,sodium salt, n-hydroxusulfosuccinimide sodium salt
PubChem CID 3520574
IUPAC Name sodium;1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate
SMILES C1C(C(=O)N(C1=O)O)S(=O)(=O)[O-].[Na+]

Specifications

Melting Point 250°C
Quantity 250 mg
Beilstein 6359129
Solubility Information Soluble in methanol and water.
Formula Weight 217.13
Percent Purity 97%
Chemical Name or Material N-Hydroxysulfosuccinimide sodium salt

Safety and Handling

Hazard Category H315-H319-H335
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only