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N-Ethylmaleimide, 99+%

Catalog No. AA4052603
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AA4052606 5 g
AA4052614 25 g
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Catalog No. AA4052603 Supplier Thermo Scientific Chemicals Supplier No. 04052603
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Description

CAS: 128-53-0 | C6H7NO2 | 125.127 g/mol

N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+ dependent internucleosomal DNA fragmentation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Chemical Identifiers

CAS 128-53-0
Molecular Formula C6H7NO2
Molecular Weight (g/mol) 125.127
MDL Number MFCD00005509
InChI Key HDFGOPSGAURCEO-UHFFFAOYSA-N
Synonym n-ethylmaleimide, ethylmaleimide, 1-ethyl-1h-pyrrole-2,5-dione, maleimide, n-ethyl, 1h-pyrrole-2,5-dione, 1-ethyl, maleic acid n-ethylimide, nem, usaf b-121, unii-o3c74acm9v, maleic acid-n-ethylimide
PubChem CID 4362
ChEBI CHEBI:44485
IUPAC Name 1-ethylpyrrole-2,5-dione
SMILES CCN1C(=O)C=CC1=O

Specifications

Melting Point 43°C to 46°C
Boiling Point 209°C to 211°C
Flash Point 73°C (163°F)
Assay Percent Range >99+%
Quantity 1 g
Beilstein 112448
Sensitivity Light sensitive
Solubility Information Soluble in ethanol,water,chloroform,methanol and toluene.
Formula Weight 125.13
Physical Form Crystalline
Chemical Name or Material N-Ethylmaleimide
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Safety and Handling

Hazard Category H300-H311-H314-H317-H335
Precautionary Statement P260-P264b-P270-P271-P272-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P501c
DOTInformation Hazard Class: 6.1; Packaging Group: II
EINECSNumber 204-892-4
RTECSNumber UX9625000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only