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Thermo Scientific Chemicals N-Acetyl-L-cysteine, 98+%

Catalog No. AAA1540936
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Catalog No. AAA1540936 Supplier Thermo Scientific Chemicals Supplier No. A1540936
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Description

N-Acetyl-L-cysteine (acetylcysteine, CAS # 616-91-1) is a product of the amino acid L-cysteine.

A mucolytic agent for isolation of mycobacteria from sputum.N-Acetyl-L-cysteine is used in the liquefaction and decontamination of sputum during the preparation for recovery of mycobacterium, which is called as Petroff's method. It shows antiviral activity against the influenza A viruses. It is used in the treatment of interstitial lung disease to prevent disease progression. It is an antioxidant, dietary supplement and protects liver. Further, it forms complexes with palladium, thereby it dissolves in water and remove palladium from drugs. Further, it is used in the treatment of paracetamol overdose. In addition to this, it is involved in the treatment of autism, Alzheimer's disease, bipolar disorder, major depressive disorder, obsessive-compulsive disorder, schizophrenia, and specific drug addictions like cocaine and cannabis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • N-Acetyl-L-cysteine (acetylcysteine) is a precursor of the antioxidant glutathione, or GSH
  • N-Acetyl-L-cysteine is cytoprotective and may prevent cancer, neurodegeneration, and other disease

Application

  • N-Acetyl-L-cysteine is useful for cellular redox study because of its anti-inflammatory properties
  • It may also be useful for psychiatric research and the study of neurodegeneration
  • It is suitable for in vivo and in vitro experiments

Chemical Identifiers

CAS 616-91-1
Molecular Formula C5H9NO3S
Molecular Weight (g/mol) 163.191
MDL Number MFCD00004880
InChI Key PWKSKIMOESPYIA-BYPYZUCNSA-N
Synonym n-acetyl-l-cysteine, acetylcysteine, n-acetylcysteine, mercapturic acid, acetadote, l-acetylcysteine, broncholysin, fluimucil, mucomyst, fluprowit
PubChem CID 12035
ChEBI CHEBI:28939
IUPAC Name (2R)-2-acetamido-3-sulfanylpropanoic acid
SMILES CC(=O)NC(CS)C(=O)O

Specifications

Melting Point 108°C to 111°C
Beilstein 1724426
Merck Index 14,88
Solubility Information Soluble in water,ethanol,methanol,dimethyl sulfoxide,hot isopropyl alcohol,methyl acetate and ethyl acetate. Insoluble in chloroform and ether.
Quantity 500 g
Optical Rotation +5.3° (c=2 in Water)
Formula Weight 163.2
Percent Purity ≥98%
Chemical Name or Material N-Acetyl-L-cysteine

Safety and Handling

EINECSNumber 210-498-3
RTECSNumber HA1660000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only