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Invitrogen™ CellROX™ Reagent Variety Pack, for oxidative stress detection

Catalog No. C10448
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Catalog No. C10448 Supplier Invitrogen™ Supplier No. C10448
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Description

For oxidative stress detection

The CellROX Variety Pack contains one vial (50μL) each of CellROXGreen Reagent, CellROXOrange Reagent, and CellROXDeep Red Reagent. These reagents are novel fluorogenic probes for measuring cellular oxidative stress in live cells. These cell-permeant dyes exhibit bright fluorescence upon oxidation by reactive oxygen species (ROS).

  • Optimized for detection of oxidative stress in live cells and may be added directly to serum-containing growth media
  • Provided as stable, ready-to-use DMSO solutions with simple protocols, compatible with standard workflows in fluorescence microscopy
  • Compatible with a variety of detection platforms, including traditional fluorescence microscopy, high content screening (HCS), and flow cytometry
  • Oxidative stress results from an imbalance between production of reactive oxygen species (ROS) and ability of cells to scavenge them
  • ROS play an important role in progression of several diseases, including inflammation, atherosclerosis, aging, and age-related degenerative disorders
  • Form: Frozen

Cell Analysis, Cell Viability, Proliferation and Function, Cellular Imaging, Flow Cytometry, Flow Cytometry Viability and Cytotoxicity Assays, Flow Cytometry of Cellular Processes, High-Content Screening (HCS), Immunofluorescence (IF), Immunofluorescence Staining and Detection, Nitro-Oxidative Stress, Reactive Oxygen Species

Order Info

Shipping Condition: Wet Ice

Specifications

Color Orange, Far-Red, Green
Format Frozen
Quantity 1 kit

Frequently Asked Questions (FAQs)

What dyes can I use to detect reactive oxygen species (ROS) in my bacteria?

Many dyes that are used on mammalian cells have also been shown to be useful in bacterial cells. For example, CellROX Deep Red Reagent has been shown to work in B. subtilis (see Reference: http://www-brs.ub.ruhr-uni-bochum.de/netahtml/HSS/Diss/RaatschenNadja/diss.pdf). If you are interested in a particular dye, but are not sure if it will work on your bacteria, literature searches are the best way to check to see if it has been tested. If not, then it may be worth testing yourself.

For Research Use Only. Not for use in diagnostic procedures.