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Milrinone, 98+%
Description
It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure. Milrinone inhibits the action of phosphodiesterase-3 preventing degradation of cAMP. The corresponding increase in cAMP levels leads to increased activation of protein kinase A. It is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure. Milrinone inhibits the action of phosphodiesterase-3 preventing degradation of cAMP. The corresponding increase in cAMP levels leads to increased activation of protein kinase A. It is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity.
Solubility
Soluble in DMSO. Insoluble in water.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure. Milrinone inhibits the action of phosphodiesterase-3 preventing degradation of cAMP. The corresponding increase in cAMP levels leads to increased activation of protein kinase A. It is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity.
Solubility
Soluble in DMSO. Insoluble in water.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Specifications
Specifications
| Melting Point | 264°C |
| Color | White |
| Quantity | 10 mg |
| UN Number | UN2811 |
| Merck Index | 14,6197 |
| Solubility Information | Soluble in DMSO; Insoluble in water. |
| Formula Weight | 211.22 |
| Percent Purity | ≥98% |
| Physical Form | Powder |
| Chemical Name or Material | Milrinone |
Safety and Handling
| Hazard Category | H301+H311+H331 |
| Hazard Statement | GHS H Statement H300-H311-H331 Fatal if swallowed. Toxic in contact with skin. Toxic if inhaled. |
| Precautionary Statement | P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P311-P312-P330-P361-P363-P501c |
| DOTInformation | Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S. |
| EINECSNumber | 278-903-6 |
| RTECSNumber | DW1762000 |
| TSCA | No |
| Recommended Storage | Ambient temperatures |
RUO – Research Use Only