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Methotrexate Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™
Supplier: Merck Emd Millipore PHR13961G
Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Methotrexate is an antagonist of folic acid that inhibits dihydrofolate reductase (DHFR) enzyme, reversibly and results in impaired DNA synthesis and cellular replication. Methotrexate has been used in treatment of rheumatoid arthritis and also for maintenance therapy in childhood acute lymphocytic leukemia (ALL).Specifications
| 59-05-2 | |
| Neat | |
| MFCD00064370 | |
| Certified Reference Material | |
| 454.44 |
| These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. | |
| C20H22N8O5 | |
| Methotrexate; (+)-Amethopterin; 4-Amino-10-methylfolic acid; 4-Amino-N10-methylpteroyl-L-glutamic acid; Antifolan; MTX; Methylaminopterin | |
| 1 g | |
| Certified Reference Material |