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Luzindole, 97%, Thermo Scientific Chemicals
A melatonin receptor antagonist
Supplier: Thermo Scientific Chemicals J61915LB0
Description
Luzindole significantly antagonizes melatonin-mediated antinociception, suggesting that MEL-1B-R plays a further role as a mediator of melatonin modulation of pain signaling. It is used both in vitro and in vivo to evaluate the roles of melatonin receptor signaling in diverse pathways, including circadian rhythms, animal behavior, and melanophore response
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsLuzindole significantly antagonizes melatonin-mediated antinociception, suggesting that MEL-1B-R plays a further role as a mediator of melatonin modulation of pain signaling. It is used both in vitro and in vivo to evaluate the roles of melatonin receptor signaling in diverse pathways, including circadian rhythms, animal behavior, and melanophore response
Solubility
Soluble in DMSO (100 mM), ethanol (100 mM), chloroform, methanol, and water.
Notes
Protect from heat. Incompatible with heat and oxidizing agents. Store at 4°C.
Specifications
| Luzindole | |
| 44°C to 46°C | |
| C19H20N2O | |
| 5 mg | |
| Soluble in DMSO (100 mM),ethanol (100 mM),chloroform,methanol,and water. | |
| CC(=O)NCCC1=C(CC2=CC=CC=C2)NC2=CC=CC=C12 | |
| 292.38 | |
| 292.37 | |
| Powder |
| 117946-91-5 | |
| White to Brown | |
| MFCD00672498 | |
| luzindole, n-acetyl-2-benzyltryptamine, 2-benzyl-n-acetyltryptamine, n-2-2-benzyl-1h-indol-3-yl ethyl acetamide, n-2-2-phenylmethyl-1h-indol-3-yl ethyl acetamide, tocris-0877, n-acetyl-2-benzyl-tryptamine, acetamide, n-2-2-phenylmethyl-1h-indol-3-yl ethyl, n-2-2-benzylindol-3-yl ethyl acetamide | |
| WVVXBPKOIZGVNS-UHFFFAOYSA-N | |
| N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide | |
| 122162 | |
| 97% |
Chemical Identifiers
| 117946-91-5 | |
| 292.38 | |
| WVVXBPKOIZGVNS-UHFFFAOYSA-N | |
| 122162 | |
| CC(=O)NCCC1=C(CC2=CC=CC=C2)NC2=CC=CC=C12 |
| C19H20N2O | |
| MFCD00672498 | |
| luzindole, n-acetyl-2-benzyltryptamine, 2-benzyl-n-acetyltryptamine, n-2-2-benzyl-1h-indol-3-yl ethyl acetamide, n-2-2-phenylmethyl-1h-indol-3-yl ethyl acetamide, tocris-0877, n-acetyl-2-benzyl-tryptamine, acetamide, n-2-2-phenylmethyl-1h-indol-3-yl ethyl, n-2-2-benzylindol-3-yl ethyl acetamide | |
| N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide |
Safety and Handling
TSCA : No
Recommended Storage : Store at -20°C
RUO – Research Use Only