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  5. L-Leucine-4-nitroanilide, 99%, Thermo Scientific Chemicals

L-Leucine-4-nitroanilide, 99%, Thermo Scientific Chemicals

Catalog No. p-7081822
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AAA1199403 1 g
AAA1199406 5 g
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Catalog No. AAA1199403 Supplier Thermo Scientific Chemicals Supplier No. A1199403
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Description

It is used to detect/evaluate functionality of amino peptidases. The compound is used in an ELISA assay to detect biological functionality of chicken amino peptidase produced by E. coli. It is also employed to characterize the native IRAP (placental leucine amino peptidase). Leu-pNA, Chromogenic Substrate is documented for use with pure samples as well as cell extracts in vitro.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used to detect/evaluate functionality of amino peptidases. The compound is used in an ELISA assay to detect biological functionality of chicken amino peptidase produced by E. coli. It is also employed to characterize the native IRAP (placental leucine amino peptidase). Leu-pNA, Chromogenic Substrate is documented for use with pure samples as well as cell extracts in vitro.

Solubility
Soluble in DMSO (>100 mM), and methanol (>25 mM).

Notes
Store away from oxidizing agents. Keep the container tightly closed in a well ventilated place.

Chemical Identifiers

CAS 4178-93-2
Molecular Formula C12H17N3O3
Molecular Weight (g/mol) 251.29
MDL Number MFCD00063681
InChI Key AXZJHDNQDSVIDR-NSHDSACASA-N
Synonym l-leucine-4-nitroanilide, h-leu-pna, l-leucine-p-nitroanilide, s-2-amino-4-methyl-n-4-nitrophenyl pentanamide, 2s-2-amino-4-methyl-n-4-nitrophenyl pentanamide, pentanamide, 2-amino-4-methyl-n-4-nitrophenyl-, s, l-leucyl-p-nitroanilide, pentanamide, 2-amino-4-methyl-n-4-nitrophenyl-, 2s, h-leu-pna.hcl, l-leu p-nitroanilide
PubChem CID 2733285
IUPAC Name (2S)-2-amino-4-methyl-N-(4-nitrophenyl)pentanamide
SMILES CC(C)C[C@H](N)C(=O)NC1=CC=C(C=C1)[N+]([O-])=O

Specifications

Melting Point 89°C to 90°C
Beilstein 2218433
Solubility Information Soluble in DMSO (>100 mM),and methanol (>25 mM).
Quantity 1 g
Formula Weight 251.29
Percent Purity 99%
Chemical Name or Material L-Leucine-4-nitroanilide

Safety and Handling

EINECSNumber 224-047-3
TSCA Yes
Recommended Storage Keep cold

RUO – Research Use Only