Recombinant Protein;Human Integrin alpha 11 beta 1 (ITGA11 & ITGB1) Heterodimer Protein;1MG;Human ITGA11 & ITGB1 Heterodimer Protein (IT1-H52W3) is expressed from human 293 cells (HEK293). It contains AA Phe 23 - Pro 1141 (ITGA11) & Gln 21-Asp 728 (ITGB1) (Accession # Q9UKX5-1 (L524R) (ITGA11) & P05556-1 (ITGB1)).;Human ITGA11 & ITGB1 Heterodimer Protein, produced by co-expression of ITGA11 and ITGB1, has a calculated MW of 131.6 kDa (ITGA11) & 82.7 kDa (ITGB1). Subunit ITGA11 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The protein migrates as 130 kDa (ITGA11) and 100 kDa (ITGB1) under reducing (R) condition (SDS-PAGE) due to glycosylation. ;Immobilized Native Human Collagen I protein at 2 g/mL (100 L/well) can bind Human ITGA11 & ITGB1 Heterodimer Protein (Cat. No. IT1-H52W3) with a linear range of 0.156-2.5 g/mL (QC tested).
