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Indomethacin, 98%

Catalog No. p-7024725
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Quantity:
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25 g
100 g
Catalog No. Quantity
AAA1991006 5 g
AAA1991014 25 g
AAA1991022 100 g
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Catalog No. AAA1991006

Supplier: Thermo Scientific Chemicals A1991006

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Description

CAS: 53-86-1 | C19H16ClNO4 | 357.79 g/mol

It is a non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. It finds its application as gout suppressant, non-steroidal anti-inflammatory drug and analgesic. It also plays many biological roles. Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.

Notes
Store away from oxidizing agents, strong bases and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Chemical Identifiers

CAS 53-86-1
Molecular Formula C19H16ClNO4
Molecular Weight (g/mol) 357.79
MDL Number MFCD00057095
InChI Key CGIGDMFJXJATDK-UHFFFAOYSA-N
Synonym indomethacin, indometacin, indocin, indometacine, indomethacine, indocid, metindol, amuno, indomethazine, imbrilon
PubChem CID 3715
ChEBI CHEBI:49662
IUPAC Name 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
SMILES CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O

Specifications

Melting Point 158°C to 161°C
Assay Percent Range 0.98
Quantity 5 g
UN Number UN2811
Beilstein 497341
Sensitivity Light sensitive
Merck Index 14,4968
Solubility Information Soluble in acetone (40mg/mL- clear,yellow solution),ethanol (20mg/mL),ether,castor oil; Soluble in chloroform (50mg/mL- clear,yellow,extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.
Formula Weight 357.8
Percent Purity 98%
Chemical Name or Material Indomethacin
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Safety and Handling

Hazard Category H300-H317-H360FD
Hazard Statement GHS H Statement
H300-H341
Precautionary Statement P201-P202-P261-P264b-P270-P272-P280g-P281-P301+P310-P302+P352-P308+P313-P330-P333+P313-P363-P501c
DOTInformation Hazard Class: 6.1; Packaging Group: II
EINECSNumber 200-186-5
RTECSNumber NL3500000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only