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Indomethacin, 98%

CAS: 53-86-1 | C19H16ClNO4 | 357.79 g/mol

$113.86 - $1064.48

Chemical Identifiers

CAS 53-86-1
Molecular Formula C19H16ClNO4
Molecular Weight (g/mol) 357.79
MDL Number MFCD00057095
InChI Key CGIGDMFJXJATDK-UHFFFAOYSA-N
Synonym indomethacin, indometacin, indocin, indometacine, indomethacine, indocid, metindol, amuno, indomethazine, imbrilon
PubChem CID 3715
ChEBI CHEBI:49662
IUPAC Name 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
SMILES CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAA1991006
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Thermo Scientific Chemicals
A1991006
5 g
Each for $113.86
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AAA1991014
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Thermo Scientific Chemicals
A1991014
25 g
Each for $360.12
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AAA1991022
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Thermo Scientific Chemicals
A1991022
100 g
Each for $1,064.48
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Description

Description

It is a non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. It finds its application as gout suppressant, non-steroidal anti-inflammatory drug and analgesic. It also plays many biological roles. Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.

Notes
Store away from oxidizing agents, strong bases and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Specifications

Chemical Identifiers

53-86-1
357.79
CGIGDMFJXJATDK-UHFFFAOYSA-N
3715
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
C19H16ClNO4
MFCD00057095
indomethacin, indometacin, indocin, indometacine, indomethacine, indocid, metindol, amuno, indomethazine, imbrilon
CHEBI:49662
CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O

Specifications

53-86-1
0.98
MFCD00057095
UN2811
Light sensitive
indomethacin, indometacin, indocin, indometacine, indomethacine, indocid, metindol, amuno, indomethazine, imbrilon
CGIGDMFJXJATDK-UHFFFAOYSA-N
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
3715
357.8
Indomethacin
158°C to 161°C
C19H16ClNO4
5 g
497341
14,4968
Soluble in acetone (40mg/mL- clear,yellow solution),ethanol (20mg/mL),ether,castor oil; Soluble in chloroform (50mg/mL- clear,yellow,extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.
CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O
357.79
CHEBI:49662
98%
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Safety and Handling

Safety and Handling

GHS H Statement
H300-H341

P201-P202-P261-P264b-P270-P272-P280g-P281-P301+P310-P302+P352-P308+P313-P330-P333+P313-P363-P501c

H300-H317-H360FD

DOTInformation : Hazard Class: 6.1; Packaging Group: II

EINECSNumber : 200-186-5

RTECSNumber : NL3500000

TSCA : Yes

Recommended Storage : Ambient temperatures

SDS
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RUO – Research Use Only