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Invitrogen™ Silencer™ Select Human Drug Targets siRNA Library

Catalog No. A30092
Encompass
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A30092 96-well Plate
A30091 384-well Plate
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Catalog No. A30092 Supplier Invitrogen™ Supplier No. A30092

Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

Description

The Silencer™ Select Human Drug Targets siRNA Library contains 23,778 Ambion™ Silencer Select highly potent and chemically-modified siRNAs targeting 7,926 genes for performing RNAi screens against known human drug target genes.

  • The Silencer™ Select Human Drug Targets siRNA Library includes genes involved in apoptosis, senescence, nucleic acid binding, autophagy, DNA repair, along with characterized nuclear receptors and other genes that are considered potential targets for therapeutics
  • The Silencer Select Human Drug Targets siRNA Library contains 23,778 Ambion™ Silencer Select highly potent and chemically-modified siRNAs targeting 7,926 genes for performing RNAi screens against known human drug target genes
  • This library was designed using the most up-to-date genome databases, including the NCBI RefSeq database
  • It is cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC)
  • The library includes gene IDs from Thermo Fisher's Human Druggable Genome and Human Extended Druggable Genome siRNA libraries that are not already in the kinase, phosphatase, protease, ion channel, GPCR or ubiquitin libraries
  • The Silencer Select siRNAs are designed using Thermo Fisher Scientific’s leading algorithms—along with our novel locked nucleic acid (LNA) chemical modifications
  • This helps to help ensure the efficacy, specificity, and potency required for RNAi screening using a comprehensive pre-defined platform for therapeutic discovery
  • Superior efficacy – Reduce off target effects by up to 90% due to latest design algorithms and LNA chemical modifications
  • Highest efficiency – Perform knockdown studies with 100-fold more potent siRNAs than currently available siRNAs
  • Dependable – Achieve faster discoveries via consistency of gene knockdown and reliability of phenotypic results
  • Convenient – Reduce data de-convolution and accelerate target validation with our 96- and 384-well arrayed format
  • Customizable – Choose the best option for workflow demands, including additional siRNA scales and pooled formats
  • Contains 0.25 nmol of each highly potent siRNA, sufficient for at least 500 transfections (at 5 nM siRNA, 100 μL transfection volume)

Specifications

Content And Storage 23,778 total siRNAs targeting 7926 genes plated onto 96-well plates (273 plates)

Store at or below -20°C in a non-frost-free freezer.
Format 96-well Plate
RNAi Type siRNA
Species Human
Sample Type RNA
For Use With (Application) RNAi
Product Line Silencer™Select
Product Type siRNA Library
Purity Standard
Quantity 1 set (96-well)
Shipping Condition Approved for shipment at Room Temperature or on Wet Ice
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