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Invitrogen™ mirVana™ miRNA Mimic, miR-1 Positive Control DFS Item

mirVana™ miRNA Mimic, miR-1 Positive Control

Supplier:  Invitrogen™ 4464063

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Catalog No. 4464063



Description

Description

miRNA mimics are small, chemically modified double-stranded RNA molecules designed to specifically bind to and mimic endogenous miRNA molecules and enable miRNA functional analysis by up-regulation of miRNA activity.

We have now released the second generation of miRNA mimics,mirVana™ miRNA Mimics which:
  • Exhibit maximum and consistent effect in vitro at low concentration
  • Are non toxic
  • Offer superior specificity due to unique Star strand modification
  • Target the most updated Sanger content
  • Can be used in vitro and in vivo, offering you consistency throughout your entire research project

    Positive and negative controls are also available for use along with mirVana™ miRNA Mimics in miRNA up-regulation experiments.

    mirVana™ miRNA Mimic miR-1 Positive Control
    The mirVana™ miRNA Mimic miR-1 Positive Control is designed to mimic mature miR-1 miRNA after delivery to mammalian cells. miR-1 is associated with down-regulation of many genes. In particular, miR-1-mediated down-regulation of Protein Tyrosine Kinase 9 (PTK9) has been shown to occur at the mRNA level. miR-1 Positive Control is intended for use as a positive control for transfection experiments using mirVana™ miRNA Mimics. Monitor activity of miR-1 Positive Control through its gene silencing of PTK9, using real-time reverse transcription-PCR to detect PTK9 mRNA.

    First Generation Mimic Controls
    Our first-generation miRNA mimics (and controls), Invitrogen™ Pre-miR™ miRNA Precursors, have lower specificity and potency, plus a lower strand specificity compared to the new mirVana™ miRNA Mimics. These first-generation mimics are recommended for completing ongoing in vitro miRNA studies. For new studies or in vivo studies, we highly recommend our new mirVana™ miRNA Mimics and their corresponding controls.
Specifications

Specifications

-20°C
miRNA & Non-Coding RNA Analysis
mirVana™ miRNA Mimic
20 nmol
mirVana™ miRNA Mimic, 20nmol, Liquid, Unconjugated Dye, Pre-miRNA RNAi Type, Positive Control Type, Used for miRNA and Non-Coding RNA Analysis, Purified Purification, –20°C Storage Temperature, For Research Use Only
Unconjugated
Purified
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

For Research Use Only. Not for use in diagnostic procedures.