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Invitrogen™ Human Torc2 Synthetic Peptide

Catalog No. PEP1590
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50 μg
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Catalog No. Quantity
PEP1590 50 μg
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Catalog No. PEP1590 Supplier Invitrogen™ Supplier No. PEP1590

Description

Synthetic Peptide

This peptide corresponds to 16 amino acid peptide near the carboxy terminus of human CRTC2. PEP-1590 can be used as a blocking peptide with polyclonal antibody PA5-34547. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37°C.

CRTC2, also known as TORC2 (Transducers Of Regulated cAMP Response Element-Binding (CREB)) 2 and the related protein CRTC1 are potent CREB coactivators that are exported from the nucleus in a CRM1-dependent manner via phosphorylation-dependent interactions. Studies suggest that their phosphorylation and nuclear/cytoplasmic shuttling play an important role in the regulation of gluconeogenesis by cAMP. CRTC2 is present in both B and T-lymphocytes and abundantly expressed in the thymus. Its activity is important in regulating the expression of genes involved in cellular energy metabolism while CRTC1 is essential for energy balance and fertility.

Specifications

Species Human
Purification Method purified
Accession Number Q53ET0
Common Name TORC2
Concentration 200 μg/mL
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Alias 4632407F12Rik; CREB regulated transcription coactivator 2; CREB-regulated transcription coactivator 2; CRTC2; mTORC2; OTTHUMP00000035255; RGD1308903; TORC2; TORC-2; transducer of CREB protein 2; transducer of regulated cAMP response element-binding protein (CREB) 2; transducer of regulated cAMP response element-binding protein 2
Gene Symbol CRTC2
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
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