missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ Human SYNE3 (aa 60-152) Control Fragment Recombinant Protein
Description
Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67444 (PA5-67444. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells. [UniProt]
Specifications
Specifications
| Accession Number | Q6ZMZ3 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 161176 |
| Name | Human SYNE3 (aa 60-152) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | C14orf139; C14orf49; KASH domain-containing protein 3; KASH3; LINC00341; Nesp3; nesprin-3; NET53; Nuclear envelope spectrin repeat protein 3; RGD1304563; spectrin repeat containing nuclear envelope family member 3; spectrin repeat containing, nuclear envelope family member 3; SYNE3 |
| Common Name | SYNE3 |
| Show More |