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Invitrogen™ Human PPAPDC1A Synthetic Peptide

Catalog No. PEP0978
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50 μg
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Catalog No. Quantity
PEP0978 50 μg
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Catalog No. PEP0978 Supplier Invitrogen™ Supplier No. PEP0978

Description

Synthetic Peptide

This peptide corresponds to 13 amino acids near the carboxy terminus of human PPAPDC1A. PEP-0978 can be used as a blocking peptide with polyclonal antibody PA5-20864.

Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide(NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. PPAPDC1A is preferentially expressed in endothelial cells. Studies of PPAPDC1A and PAP activity suggest that they may play a role in angiogenesis.

Specifications

Species Human
Purification Method purified
Accession Number Q5VZY2
Common Name PPAPDC1A
Concentration 200 μg/mL
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Alias C030048B12Rik; diacylglycerol pyrophosphate like 2; diacylglycerol pyrophosphate phosphatase-like 2; DPPL2; Gm1090; phosphatidate phosphatase PPAPDC1A; phosphatidic acid phosphatase type 2 domain containing 1A; phosphatidic acid phosphatase type 2 domain-containing protein 1A; Phospholipid phosphatase 4; PLPP4; PPAPDC1; Ppapdc1a; RGD1306289; RP11-257O17.1
Gene Symbol PLPP4
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
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