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Invitrogen™ Human Pellino 1 Synthetic Peptide

Catalog No. PEP1507
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50 μg
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Catalog No. Quantity
PEP1507 50 μg
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Catalog No. PEP1507 Supplier Invitrogen™ Supplier No. PEP1507
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Description

Synthetic Peptide

Pellino 1 Synthetic Peptide, PEP-1507, from Invitrogen.

The Pellino proteins are a highly homologous family of E3 ubiquitin ligases that act as upstream mediators in Toll-like receptor (TLR) pathways that lead to activation of MAP kinases and transcription factors. Pellino 1 is required for interleukin-1-mediated signaling through its interaction with the IRAK4-IRAK-TRAF6 complex, ultimately resulting in the activation of NF-Kappa-B. Like other members of the Pellino family, Pellino 1 is an E3 ubiquitin ligase, able to catalyze the polyubiquitination of IRAK1. It is activated via phosphorylation by either IRAK1 and IRAK4 or the IKK-related kinases IKK-epsilon; and TBK1. In addition to phosphorylation, Pellino 1 activity is also modulated via ubiquitination and sumoylation.

Specifications

Gene ID (Entrez) 57162
Species Human
Purification Method purified
Accession Number Q96FA3
Common Name Human Pellino 1
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol PELI1
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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