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Invitrogen™ Human ORAI2 Synthetic Peptide

Catalog No. PEP0486
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50 μg
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Catalog No. Quantity
PEP0486 50 μg
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Catalog No. PEP0486 Supplier Invitrogen™ Supplier No. PEP0486

Description

Synthetic Peptide

This peptide corresponds to 15 amino acids near the carboxy terminus of human ORAI2. PEP-0486 can be used as a blocking peptide with polyclonal antibody PA5-20369.

Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.

Specifications

Species Human
Purification Method purified
Accession Number Q96SN7
Common Name ORAI2
Concentration 200 μg/mL
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Alias A730041O15Rik; C7orf19; calcium release-activated calcium channel 2; calcium release-activated calcium modulator 2 protein; CAP-binding protein complex interacting protein 2; CAP-binding protein complex-interacting protein 2; CBCIP2; H_NH0514P08.8; MEM142B; ORAI calcium release-activated calcium modulator 2; ORAI2; PP1729; Protein orai-2; putative protein ORAI2-2; RGD1310213; TMEM142B; Transmembrane protein 142B
Gene Symbol ORAI2
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
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