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Invitrogen™ Human Kinesin 5B (aa 376-396) Synthetic Peptide

Catalog No. PEP198
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50 μg
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Catalog No. Quantity
PEP198 50 μg
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Catalog No. PEP198 Supplier Invitrogen™ Supplier No. PEP198

Description

Synthetic Peptide

PEP-198 is a 18 amino acid synthetic peptide corresponding to amino acid residues 376-396 from human kinesin 5B. The sequence of this peptide is (amino to carboxy terminus): C I D E Q F D K E K A N L E A F T V D K D I. This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, catalog # PA1-643. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions. Reconstitute with 0.1 mL of distilled water.

Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.

Specifications

Gene ID (Entrez) 3799
Species Human
Purification Method purified
Accession Number P33176
Common Name Kinesin 5B
Concentration 0.5 mg/mL
Content And Storage -20°C. Avoid freeze-thaw cycles.
Description Synthetic Peptide
Format Lyophilized
Formulation Peptide with no preservative
For Use With (Application) Control
Gene Alias AL022807; Conventional kinesin heavy chain; EMBL:ABC25059.1}; epididymis secretory protein Li 61; HEL-S-61; Khc; Khcs; KIF5A; KIF5B; kif5b {ECO:0000312; kinesin 1 (110-120kD); kinesin family member 5A; kinesin family member 5B; kinesin heavy chain; kinesin heavy chain member 5B, ubiquitous; kinesin-1 heavy chain; KINH; KNS; Kns1; ubiquitous kinesin heavy chain; UKHC; U-KHC; Unknown (protein for IMAGE:7944745)
Gene Symbol KIF5B
Lyophilized Yes
Preservative No preservative
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
Sequence C I D E Q F D K E K A N L E A F T V D K D I
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