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Invitrogen™ Human Histone H1.1 (aa 116-154) Control Fragment Recombinant Protein
Description
Highest antigen sequence indentity to the following orthologs: Mouse (55%), Rat (55%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111188 (PA5-111188. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Specifications
Specifications
| Accession Number | Q02539 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 3024 |
| Name | Human Histone H1.1 (aa 116-154) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | H1 histone family, member 1; H1.1; H1-1; H1A; H1F1; HIST1; HIST1H1A; histone 1, H1a; histone cluster 1, H1a; histone H1.1; Histone H1a |
| Common Name | Histone H1.1 |
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